Virtual reality exposure therapy for sexual aversion: a proof-of-concept study on acceptability, adequacy, and clinical effects.

IF 3.3 3区 医学 Q1 UROLOGY & NEPHROLOGY Journal of Sexual Medicine Pub Date : 2025-01-03 DOI:10.1093/jsxmed/qdae154
David Lafortune, Valérie A Lapointe, Simon Dubé, Jonathan Bonneau
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Abstract

Background: Sexual dysfunctions impair the intimate relationships of up to one-third of the population. Virtual reality (VR) offers innovative treatment options for both mental and sexual disorders, such as female orgasmic disorder and erectile disorder. Sexual aversion disorder (SAD)-the anxiety, disgust, and avoidance of sexual contexts-is a chronic condition commonly treated with anxiety-reducing strategies, such as exposure-based therapy. Despite exposure's efficacy in reducing SAD symptoms, VR exposure therapy's (VRET) effectiveness remains unexplored for this condition.

Aim: This proof-of-concept study examines the acceptability, adequacy, and clinical effects of a VRET's simulation protocol for SAD.

Methods: In the laboratory, 15 adults suffering from SAD (Mage = 35.00; SD = 11.36) viewed 15 virtual sexual scenarios of increasing intensity (eg, flirting, nudity, genital stimulation) adjusted to their sexual preferences and gender identities.

Outcomes: Levels of anxiety, disgust, and catastrophizing beliefs were measured throughout the scenarios using standard self-report measures. Participants also completed validated questionnaires on sexual presence and simulation realism, as well as open-ended questions on scenarios' representativeness and adequacy immediately after immersion. Six months after the laboratory visit, participants completed a negative effects questionnaire and were screened for SAD symptoms again. Repeated-measures ANOVAs and descriptive analyses were performed.

Results: Levels of anxiety and disgust significantly increased with the intensity of sexual scenarios. Catastrophizing levels were high and tended to augment with increasing exposure levels. A significant reduction in symptoms of SAD was found from pre-simulation to the 6-month follow-up assessment. Sexual presence and realism scores were moderate. Qualitative assessment revealed that all participants reported the sexual scenarios were representative of real-life situations that tend to elicit SAD symptoms for them. Reported negative effects were generally mild.

Clinical implications: This proof-of-concept study suggests that VRET may have the potential to elicit self-reported emotional and cognitive manifestations of SAD (sex-related anxiety, disgust, and catastrophizing), while also hinting at its acceptability, adequacy, and benefits in alleviating SAD symptoms.

Strengths & limitations: While this study marks the first exploration of the clinical relevance of gender-inclusive virtual sexual scenarios for SAD, its design and sample composition may impact observed effects and the generalizability of findings.

Conclusion: This study invites future clinical trials to assess VRET efficacy for SAD.

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虚拟现实暴露疗法治疗性厌恶:关于可接受性、充分性和临床效果的概念验证研究。
背景:性功能障碍损害了多达三分之一人口的亲密关系。虚拟现实(VR)为精神障碍和性障碍(如女性性高潮障碍和勃起障碍)提供了创新的治疗方案。性厌恶障碍(SAD)--对性环境的焦虑、厌恶和回避--是一种慢性疾病,通常采用减少焦虑的策略进行治疗,如暴露疗法。尽管暴露疗法能有效减轻 SAD 症状,但虚拟现实暴露疗法(VRET)对这种病症的疗效仍有待探索。目的:本概念验证研究探讨了虚拟现实暴露疗法模拟方案治疗 SAD 的可接受性、充分性和临床效果:在实验室中,15 名患有 SAD 的成年人(Mage = 35.00;SD = 11.36)观看了 15 个根据其性偏好和性别认同调整的、强度不断增加的虚拟性场景(如调情、裸体、生殖器刺激):采用标准的自我报告测量方法,对整个场景中的焦虑、厌恶和灾难化信念水平进行测量。参与者还填写了关于性存在和模拟逼真度的有效问卷,以及关于情景模拟的代表性和充分性的开放式问题。实验室访问结束六个月后,参与者填写了一份负面影响问卷,并再次接受了 SAD 症状筛查。研究人员进行了重复测量方差分析和描述性分析:结果:焦虑和厌恶程度随着性场景的强度而明显增加。灾难化程度较高,并有随着暴露程度的增加而增强的趋势。从模拟前到 6 个月随访评估期间,SAD 症状明显减少。性临场感和逼真度得分处于中等水平。定性评估显示,所有参与者都报告说,性爱场景代表了现实生活中容易引发他们 SAD 症状的情况。所报告的负面影响一般较轻:这项概念验证研究表明,VRET 有可能诱发自述的 SAD 情绪和认知表现(与性有关的焦虑、厌恶和灾难化),同时也暗示了其可接受性、适当性以及在缓解 SAD 症状方面的益处:虽然本研究首次探索了性别包容的虚拟性场景对 SAD 的临床意义,但其设计和样本组成可能会影响观察效果和研究结果的普遍性:结论:本研究为未来的临床试验提供了参考,以评估虚拟性情境疗法对 SAD 的疗效。
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来源期刊
Journal of Sexual Medicine
Journal of Sexual Medicine 医学-泌尿学与肾脏学
CiteScore
6.20
自引率
5.70%
发文量
826
审稿时长
2-4 weeks
期刊介绍: The Journal of Sexual Medicine publishes multidisciplinary basic science and clinical research to define and understand the scientific basis of male, female, and couples sexual function and dysfunction. As an official journal of the International Society for Sexual Medicine and the International Society for the Study of Women''s Sexual Health, it provides healthcare professionals in sexual medicine with essential educational content and promotes the exchange of scientific information generated from experimental and clinical research. The Journal of Sexual Medicine includes basic science and clinical research studies in the psychologic and biologic aspects of male, female, and couples sexual function and dysfunction, and highlights new observations and research, results with innovative treatments and all other topics relevant to clinical sexual medicine. The objective of The Journal of Sexual Medicine is to serve as an interdisciplinary forum to integrate the exchange among disciplines concerned with the whole field of human sexuality. The journal accomplishes this objective by publishing original articles, as well as other scientific and educational documents that support the mission of the International Society for Sexual Medicine.
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