Eduardo V. Bergmann , Ana P.B. Cavalaro , Newller M. Kimura , Vitor S. Zanuto , Nelson G.C. Astrath , Leandro S. Herculano , Luis C. Malacarne
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引用次数: 0
Abstract
The growing interest in using photodynamic therapy for cancer treatment and antimicrobial applications has prompted the search for different classes of dyes. In general, the protocols of these studies are different, making it difficult to compare their efficiency directly. Here, we apply a controlled protocol to analyze the photophysical properties of Erythrosin B, Eosin Y, and Rose Bengal using a set of optical techniques. The results show that Erythrosine has the best singlet oxygen generation capacity. This result, added to the well-known low toxicity of Erythrosine, makes it a good choice among the xanthenes for health applications.
人们对利用光动力疗法治疗癌症和抗菌的兴趣与日俱增，这促使人们寻找不同类别的染料。一般来说，这些研究的方案各不相同，因此很难直接比较它们的效率。在此，我们采用一套受控方案，利用一系列光学技术分析了红霉素 B、曙红 Y 和玫瑰红的光物理特性。结果表明，赤藓红的单线态氧生成能力最强。这一结果，加上众所周知的赤藓红的低毒性，使其成为健康应用领域呫吨中的一个不错选择。
期刊介绍：
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science.
The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments.
Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate.
Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to:
Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences,
Novel experimental techniques or instrumentation for molecular spectroscopy,
Novel theoretical and computational methods,
Novel applications in photochemistry and photobiology,
Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.
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