Effect of POD24 on the prognosis of follicular and other indolent B-cell non-hodgkin lymphomas

IF 2.3 3区 医学 Q2 HEMATOLOGY Annals of Hematology Pub Date : 2024-11-16 DOI:10.1007/s00277-024-06079-y
Xiaoyan Li, Xin Wang
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Abstract

Does the presence of POD24 serve as a reliable prognostic factor for adverse outcomes in all individuals diagnosed with B-cell indolent lymphoma?

The interrelationship between POD24 and these prognostic assessment tools.

The pathogenesis of early disease progression.

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POD24对滤泡性淋巴瘤和其他轻度B细胞非霍奇金淋巴瘤预后的影响。
惰性B细胞非霍奇金淋巴瘤(B-NHL)是一类异质性淋巴瘤,具有多种病理亚型。随着利妥昔单抗化疗免疫疗法(R-chemo)的应用,患者的预后大大改善,10 年生存率达到 60-80%。尽管取得了这些进展,但仍有相当多的患者在初始治疗期间或治疗后不久出现疾病进展。那些在最初 24 个月(POD24)内病情恶化的患者的预后仍然明显较差。本研究旨在通过全面的文献综述,探讨POD24在预测不同亚型轻度B细胞NHL预后方面的意义。调查还包括研究现有的预后评估工具,并评估 POD24 与这些工具之间的相互关系。通过综合相关的研究结果,本研究旨在帮助人们更好地理解POD24在预后评估中的作用及其在指导轻度B细胞NHL患者临床决策中的潜在意义。
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来源期刊
Annals of Hematology
Annals of Hematology 医学-血液学
CiteScore
5.60
自引率
2.90%
发文量
304
审稿时长
2 months
期刊介绍: Annals of Hematology covers the whole spectrum of clinical and experimental hematology, hemostaseology, blood transfusion, and related aspects of medical oncology, including diagnosis and treatment of leukemias, lymphatic neoplasias and solid tumors, and transplantation of hematopoietic stem cells. Coverage includes general aspects of oncology, molecular biology and immunology as pertinent to problems of human blood disease. The journal is associated with the German Society for Hematology and Medical Oncology, and the Austrian Society for Hematology and Oncology.
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