Plasmon-enhanced NIR-II photoluminescence of rare-earth oxide nanoprobes for high-sensitivity optical temperature sensing.

Abstract

With ongoing advancements in photothermal therapy, achieving efficient tumor cell eradication while minimizing damage to healthy tissues necessitates a highly effective and non-invasive real-time temperature monitoring technique for human tissues. Herein, we report a near-infrared (NIR)-II optical temperature sensing nanoprobe featuring rare-earth-doped gadolinium oxide nanocrystals (RENCs) attached to the dumbbell mesoporous silica-coated gold nanorods (AuNRs). The composite nanoprobe presents an intense absorption in the NIR region, and NIR-II photoluminescence (PL) increases by 97.2 to 102-fold compared to pure RENCs upon 980 nm irradiation. The localized electric field generated through surface plasmon resonance effects of AuNRs demonstrated a dumbbell-shaped distribution that aligns with the structure of nanoprobes, maximizing the PL enhancement of RENCs. Moreover, the NIR-II emissions are changed with the rising temperature, with an exceptional relative sensitivity of 7.25% K^-1 at 338 K based on PL lifetime, indicating the nanoprobe is highly potential for optical temperature sensing.