Chemical Constituents of Seriphidium transiliense and Their Anti-Inflammatory Activity

IF 0.8 4区 化学 Q4 CHEMISTRY, MEDICINAL Chemistry of Natural Compounds Pub Date : 2024-11-06 DOI:10.1007/s10600-024-04507-z
F. Wang, H. Wen, L. Liu, F. He, X. Xin
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Abstract

Seven compounds were isolated from Seriphidium transiliense, of which 1–5 and 7 were obtained for the first time. Compound 1 was a new natural compound that was previously synthesized. Compounds 4, 5, and 7 in LPS-stimulated BV2 cells inhibited the NO content with IC50 42.24, 44.03, and 35.67 μM, respectively.

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Seriphidium transiliense 的化学成分及其抗炎活性
从Seriphidium transiliense中分离出了7种化合物,其中1-5和7是首次获得。化合物 1 是以前合成的一种新的天然化合物。化合物 4、5 和 7 在 LPS 刺激的 BV2 细胞中抑制 NO 的含量,IC50 分别为 42.24、44.03 和 35.67 μM。
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来源期刊
Chemistry of Natural Compounds
Chemistry of Natural Compounds 化学-有机化学
CiteScore
1.40
自引率
25.00%
发文量
265
审稿时长
7.8 months
期刊介绍: Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.
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