Hardware Complication Risks in Head and Neck Cancer Patients Undergoing Reconstructive Surgery With Segmental Mandibulectomy.

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2024-11-18 DOI:10.1002/hed.28000

Kevin Yu-Ting Chen, Angela Chien-Yu Chen, Chung-Kan Tsao, Shao-Yu Hung, David Chon-Fok Cheong, Huang-Kai Kao

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Abstract

Background: The primary objective of this study was to ascertain the risk factors associated with hardware complications following segmental mandibular reconstruction in head and neck cancer patients. Additionally, we sought to develop a nomogram model that enables accurate risk prediction.

Methods: Patients who underwent segmental mandibulectomy with immediate free or local regional tissue transfer between January 2016 and December 2020 were reviewed. Hardware complications were defined. Patient demographics and perioperative parameters were analyzed.

Results: A total of 510 patients were analyzed. Postoperative radiation therapy (OR = 2.296, 95% CI = 1.339-3.938, p = 0.003), postoperative wound infection (OR = 2.367, 95% CI = 1.472-3.806, p < 0.001), and debridement for flap-related complications (OR = 5.484, 95% CI = 3.269-9.199, p < 0.001) were identified as independent risk factors. The nomogram model demonstrated good discriminatory ability.

Conclusion: This comprehensive analysis identified three independent risk factors, and the nomogram provides a valuable tool for predicting the risks. Further research is needed to validate these findings and explore preventive strategies.

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头颈部癌症患者接受下颌骨节段切除整形手术的硬件并发症风险。

背景：本研究的主要目的是确定与头颈部癌症患者下颌骨节段重建后硬件并发症相关的风险因素。此外，我们还试图建立一个能准确预测风险的提名图模型：方法：我们对 2016 年 1 月至 2020 年 12 月间接受下颌骨节段切除术并立即进行游离或局部区域组织转移的患者进行了回顾性研究。定义了硬件并发症。结果：共分析了510例患者：结果：共分析了510名患者。术后放射治疗（OR = 2.296，95% CI = 1.339-3.938，P = 0.003）、术后伤口感染（OR = 2.367，95% CI = 1.472-3.806，P 结论：该分析确定了三个独立的风险因素：这项综合分析确定了三个独立的风险因素，提名图为预测风险提供了一个有价值的工具。需要进一步的研究来验证这些发现并探索预防策略。

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.