{"title":"A resurfaced sensor NLR confers new recognition specificity to non-MAX effectors","authors":"Tongtong Zhu, Xuefeng Wu, Guixin Yuan, Dongli Wang, Vijai Bhadauria, You-Liang Peng, Junfeng Liu, Xin Zhang","doi":"10.1111/jipb.13805","DOIUrl":null,"url":null,"abstract":"<p>Replacing the HMA domain of the rice (<i>Oryza sativa</i>) immune receptor RGA5 with that of the rice HMA DOMAIN-CONTAINING PROTEIN 120 (HMA120) creates a designer RGA5<sup>HMA120</sup> that confers resistance to <i>Magnaporthe oryzae</i> isolates expressing the non-MAX effector gene <i>AVR-Pita</i>, thus enabling the generation of new synthetic resistance genes.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":195,"journal":{"name":"Journal of Integrative Plant Biology","volume":"67 1","pages":"11-14"},"PeriodicalIF":9.3000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jipb.13805","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Integrative Plant Biology","FirstCategoryId":"99","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jipb.13805","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Replacing the HMA domain of the rice (Oryza sativa) immune receptor RGA5 with that of the rice HMA DOMAIN-CONTAINING PROTEIN 120 (HMA120) creates a designer RGA5HMA120 that confers resistance to Magnaporthe oryzae isolates expressing the non-MAX effector gene AVR-Pita, thus enabling the generation of new synthetic resistance genes.
期刊介绍：
Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.
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