Comprehensive insight into recent algal enzymes production and purification advances: Toward effective commercial applications: A review.

IF 7.7 1区 化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY International Journal of Biological Macromolecules Pub Date : 2024-11-16 DOI:10.1016/j.ijbiomac.2024.137783
Esmail M El-Fakharany, Ahmed K Saleh, Yousra A El-Maradny, Mohamed H El-Sayed, Ibtisam Alali, Alaa Muqbil Alsirhani, Adel I Alalawy, Aliyah S Alhawiti, Ibrahim Saleem Alatawi, Wafa Mazi, Hamada El-Gendi
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Abstract

Algal enzymes are essential catalysts in numerous biological reactions and industrial processes owing to their adaptability and potency. The marketing of algal enzymes has recently risen due to various reasons, including the cost-efficient manner of their cultivation in photobioreactors, the eco-friendly production of high biomass contents, sources of novel enzymes that used in many sectors (biofuel and bioremediation applications), sustainability, and more renewability. Oxidoreductases and hydrolytic enzymes are among the important applied algal enzymes in industrial applications, with annually growing demand. These algal enzymes have opened up new avenues for significant health advantages in reducing and treating oxidative stress, cardiovascular illness, tumors, microbial infections, and viral outbreaks. Despite their promising uses, commercial applications of algal enzymes face many difficulties, such as stability, toxicity, and lower data availability on specific and adequate catalytic mechanisms. Therefore, this review focuses on the algal enzyme types, their uses and advantages over other microbial enzymes, downstream and upstream processing, their commercial and marketing, and their challenges. With the constant development of novel enzymes and their uses, enzyme technology provides exciting options for several industrial sectors.

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全面了解最近在藻类酶生产和纯化方面取得的进展:实现有效的商业应用:综述。
藻类酶由于其适应性和效力,在许多生物反应和工业过程中是必不可少的催化剂。近来,藻类酶的销售量有所上升,原因有很多,包括在光生物反应器中培养藻类酶的成本效益高、高生物质含量的生态友好型生产、可用于许多领域(生物燃料和生物修复应用)的新型酶的来源、可持续性和更多的可再生性。氧化还原酶和水解酶是工业应用中重要的藻类酶之一,需求量每年都在增长。这些藻类酶为减少和治疗氧化应激、心血管疾病、肿瘤、微生物感染和病毒爆发等重大健康问题开辟了新途径。尽管藻类酶的用途前景广阔,但其商业应用也面临着许多困难,如稳定性、毒性以及有关特定和适当催化机理的数据较少。因此,本综述侧重于海藻酶的类型、其用途和与其他微生物酶相比的优势、下游和上游加工、其商业和营销及其挑战。随着新型酶及其用途的不断发展,酶技术为多个工业部门提供了令人兴奋的选择。
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来源期刊
International Journal of Biological Macromolecules
International Journal of Biological Macromolecules 生物-生化与分子生物学
CiteScore
13.70
自引率
9.80%
发文量
2728
审稿时长
64 days
期刊介绍: The International Journal of Biological Macromolecules is a well-established international journal dedicated to research on the chemical and biological aspects of natural macromolecules. Focusing on proteins, macromolecular carbohydrates, glycoproteins, proteoglycans, lignins, biological poly-acids, and nucleic acids, the journal presents the latest findings in molecular structure, properties, biological activities, interactions, modifications, and functional properties. Papers must offer new and novel insights, encompassing related model systems, structural conformational studies, theoretical developments, and analytical techniques. Each paper is required to primarily focus on at least one named biological macromolecule, reflected in the title, abstract, and text.
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