GenBank 2025 update.

IF 16.6 2区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Nucleic Acids Research Pub Date : 2024-11-18 DOI:10.1093/nar/gkae1114
Eric W Sayers, Mark Cavanaugh, Linda Frisse, Kim D Pruitt, Valerie A Schneider, Beverly A Underwood, Linda Yankie, Ilene Karsch-Mizrachi
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Abstract

GenBank® (https://www.ncbi.nlm.nih.gov/genbank/) is a comprehensive, public data repository that contains 34 trillion base pairs from over 4.7 billion nucleotide sequences for 581 000 formally described species. Daily data exchange with the European Nucleotide Archive and the DNA Data Bank of Japan ensures worldwide coverage. We summarize the content of the database in 2025 and recent updates such as accelerated processing of influenza sequences and the ability to upload feature tables to Submission Portal for messenger RNA sequences. We provide an overview of the web, application programming and command-line interfaces that allow users to access GenBank data. We also discuss the importance of creating BioProject and BioSample records during submissions, particularly for viruses and metagenomes. Finally, we summarize educational materials and recent community outreach efforts.

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GenBank 2025 更新。
GenBank® (https://www.ncbi.nlm.nih.gov/genbank/) 是一个全面的公共数据储存库,包含 581 000 个正式描述物种的 47 亿多个核苷酸序列中的 34 万亿个碱基对。与欧洲核苷酸档案馆和日本 DNA 数据库的日常数据交换确保了数据的全球覆盖。我们总结了 2025 年数据库的内容和最近的更新,如流感序列的加速处理和向提交门户网站上传信使 RNA 序列特征表的功能。我们概述了允许用户访问 GenBank 数据的网络、应用程序编程和命令行界面。我们还讨论了在提交过程中创建生物项目和生物样本记录的重要性,尤其是病毒和元基因组。最后,我们总结了教育材料和近期的社区推广工作。
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来源期刊
Nucleic Acids Research
Nucleic Acids Research 生物-生化与分子生物学
CiteScore
27.10
自引率
4.70%
发文量
1057
审稿时长
2 months
期刊介绍: Nucleic Acids Research (NAR) is a scientific journal that publishes research on various aspects of nucleic acids and proteins involved in nucleic acid metabolism and interactions. It covers areas such as chemistry and synthetic biology, computational biology, gene regulation, chromatin and epigenetics, genome integrity, repair and replication, genomics, molecular biology, nucleic acid enzymes, RNA, and structural biology. The journal also includes a Survey and Summary section for brief reviews. Additionally, each year, the first issue is dedicated to biological databases, and an issue in July focuses on web-based software resources for the biological community. Nucleic Acids Research is indexed by several services including Abstracts on Hygiene and Communicable Diseases, Animal Breeding Abstracts, Agricultural Engineering Abstracts, Agbiotech News and Information, BIOSIS Previews, CAB Abstracts, and EMBASE.
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