Isolation and genome characterization of a Klebsiella pneumoniae clinical strain carrying blaNDM-5 and blaOXA-48 isolated in Italy.

IF 1.5 4区 医学 Q4 MICROBIOLOGY New Microbiologica Pub Date : 2024-11-01
Stefano Amadesi, Erica Diani, Annarita Mazzariol, Davide Gibellini, Paolo Gaibani
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引用次数: 0

Abstract

Carbapenemase-producing Enterobacteriales (CPE) represent an emerging threat for global public health and a serious problem for clinicians due to the limited available treatment options. The emergence of CPE has been recently described worldwide by describing different antimicrobial mechanisms. Here, we describe a CPE carrying dual-carbapenemase isolated in Italy and we provide a deep characterization of the antimicrobial resistance genes, virulence-factors and prophage regions within the genome.

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在意大利分离到的携带 blaNDM-5 和 blaOXA-48 的肺炎克雷伯氏菌临床菌株的分离和基因组特征。
产碳青霉烯酶肠杆菌(CPE)是全球公共卫生面临的一个新威胁,也是临床医生面临的一个严重问题,因为可用的治疗方案有限。最近,世界各地通过描述不同的抗菌机制来描述 CPE 的出现。在此,我们描述了在意大利分离到的一种携带双碳酸烯酵素酶的 CPE,并对其基因组中的抗菌耐药基因、毒力因子和噬菌体区域进行了深入分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
New Microbiologica
New Microbiologica 生物-微生物学
CiteScore
2.20
自引率
5.60%
发文量
40
审稿时长
6-12 weeks
期刊介绍: The publication, diffusion and furtherance of research and study on all aspects of basic and clinical Microbiology and related fields are the chief aims of the journal.
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