{"title":"Brain-penetrating molecule might offer a route to treat glioblastoma tumours","authors":"Mushtaq A. Nengroo, \n Issam Ben-Sahra","doi":"10.1038/d41586-024-03556-2","DOIUrl":null,"url":null,"abstract":"Gliocidin can target brain tumours by disrupting the production of nucleotides needed for cell growth. The molecule’s unusual ability to cross the blood–brain barrier suggests a promising way to develop therapies. Molecule targeting brain tumours disrupts nucleotide production.","PeriodicalId":18787,"journal":{"name":"Nature","volume":"636 8042","pages":"307-308"},"PeriodicalIF":48.5000,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature","FirstCategoryId":"103","ListUrlMain":"https://www.nature.com/articles/d41586-024-03556-2","RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Gliocidin can target brain tumours by disrupting the production of nucleotides needed for cell growth. The molecule’s unusual ability to cross the blood–brain barrier suggests a promising way to develop therapies. Molecule targeting brain tumours disrupts nucleotide production.
期刊介绍：
Nature is a prestigious international journal that publishes peer-reviewed research in various scientific and technological fields. The selection of articles is based on criteria such as originality, importance, interdisciplinary relevance, timeliness, accessibility, elegance, and surprising conclusions. In addition to showcasing significant scientific advances, Nature delivers rapid, authoritative, insightful news, and interpretation of current and upcoming trends impacting science, scientists, and the broader public. The journal serves a dual purpose: firstly, to promptly share noteworthy scientific advances and foster discussions among scientists, and secondly, to ensure the swift dissemination of scientific results globally, emphasizing their significance for knowledge, culture, and daily life.
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