Anemias hemolíticas adquiridas y congénitas

Abstract

Hemolytic anemias are a heterogeneous group of diseases characterized by a decrease in red blood cell survival (hemolysis). They are regenerative anemias (reticulocytosis) not justified by bleeding or recent correction of maturation factors deficits and which show signs of accelerated erythrocyte destruction, such as increased indirect bilirubin and lactate dehydrogenase (LDH) and decreased haptoglobin as well as morphological abnormalities on a peripheral blood smear. There are multiple causes of hemolytic anemia, including both acute and chronic congenital and acquired diseases. They are of varying potential severity. The intensity of the clinical signs and symptoms depends on the degree and speed of anemia onset. A good etiological diagnosis is fundamental in order to establish the proper treatment, given that each requires specific management.