Treating cancer with a new smart drug delivery system

IF 5.9 3区 农林科学 Q1 VETERINARY SCIENCES Lab Animal Pub Date : 2024-11-26 DOI:10.1038/s41684-024-01480-6
Jorge Ferreira
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用新型智能给药系统治疗癌症
抗肿瘤药物对癌症治疗至关重要,但它们缺乏特异性,不仅会杀死癌细胞,也会杀死健康细胞。癌症治疗面临的另一个挑战是耐药性的产生,从而导致药物失效。科学报告》(Scientific Reports)上的一项研究显示,利用纳米技术开发出了一种智能给药系统,可将抗肿瘤药物特异性地输送到 Balb/c 小鼠的肿瘤中。与游离的多西他赛(DTX)相比,这种方法用更小的剂量就能有效治疗小鼠的乳腺癌。与游离药物相比,这些纳米颗粒不仅对癌细胞的细胞毒性更强,而且还能显著减少癌细胞的转移。这些结果表明,这是一种很有前景的癌症药物递送替代方法。使用这种智能给药系统可以创造出副作用更小的更有效的治疗方法,从而更好地治疗癌症:Taghipour, Y.D. et al. 科学报告 14, 24603 (2024)
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来源期刊
Lab Animal
Lab Animal 农林科学-兽医学
CiteScore
0.60
自引率
2.90%
发文量
181
审稿时长
>36 weeks
期刊介绍: LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.
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