Mauro Di Stasi, Valentina Parisi, Vanessa Hernandez, Erica Gazzillo, Maria Giovanna Chini, Giuseppe Bifulco, Alessandra Braca, Giuliana Donadio, Nunziatina De Tommasi
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引用次数: 0
Abstract
The phytochemical study of Zanthoxylum rhoifolium apolar and medium polarity stem bark and leaves extracts afforded twenty-nine compounds, including three new sesquiterpenes (1: -3: ) and one new α-ionone glycoside (4: ). All compounds were characterized by means of 1D and 2D NMR and HRESIMS data. Furthermore, a precise structural analysis was performed, employing a combined density functional theory (DFT)/NMR approach to elucidate the compounds configuration. The crude extracts were then tested against a panel of Gram-positive and Gram-negative bacteria, by broth dilution methods to determine their minimal inhibitory concentration (MIC); in these experimental conditions no interesting antimicrobial activity was observed.
期刊介绍：
Planta Medica is one of the leading international journals in the field of natural products – including marine organisms, fungi as well as micro-organisms – and medicinal plants. Planta Medica accepts original research papers, reviews, minireviews and perspectives from researchers worldwide. The journal publishes 18 issues per year.
The following areas of medicinal plants and natural product research are covered:
-Biological and Pharmacological Activities
-Natural Product Chemistry & Analytical Studies
-Pharmacokinetic Investigations
-Formulation and Delivery Systems of Natural Products.
The journal explicitly encourages the submission of chemically characterized extracts.
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