Deciphering versatile electrode materials in the electrochemical progressive processes for flutamide detection: A systematic review

IF 4.9 2区化学 Q1 CHEMISTRY, ANALYTICAL Microchemical Journal Pub Date : 2024-11-22 DOI:10.1016/j.microc.2024.112244

Chellapandi Bhuvaneswari , Karuppaiya Palpandi , Boopathi Shagunthala Hariprasad , Chettipalayam Arunasalam Dhayanithi , Natarajan Raman , Periakaruppan Prakash , Sundaram Ganesh Babu

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Abstract

Excess of flutamide causes diseases, therefore excess of anything is undesirable. In order to safeguard human health and the environment, the scientific community battled to monitor hazardous and deadly substances, bacteria, gases, and radiation. So, we focus on the detection of Flutamide (FLT), a non-steroidal anti-androgen drug that is widely used in the treatment of prostatic carcinoma are rapidly attracted interest in the field of medical sciences because it is cherished in monitoring health and environmental conditions and their absurd negative effects when used in excess. This review article focuses on the important advancement in developing mixed and clinical nano samples-based on electrochemical sensors for simultaneous electrochemical sensing of FLT. The fabrication of different electrodes such as Diamond Electrode, Screen Printed Carbon Electrodes (SPCE), Glassy Carbon Electrode (GCE), Gold Electrode (AuE), Carbon Paste Electrode (CPE), and Graphite Pencil Lead Electrode used to detect FLT are highlighted. Furthermore, the challenges of translating different kinds of electrodes with supported nanomaterials-based sensors from the laboratory to the market are considered in future perspectives. This review discusses the selective reports on the different kinds of electrodes to discuss the application of FLT sensors during the period from 2012 to 2024. This review will be a useful tool for researchers, providing new perspectives and ideas for exciting new directions to explore.

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解密氟他胺检测电化学递进过程中的多功能电极材料：系统综述

过量的氟他胺会导致疾病，因此任何东西过量都是不可取的。为了保护人类健康和环境，科学界一直致力于监测有害和致命物质、细菌、气体和辐射。氟他胺（FLT）是一种非甾体抗雄激素药物，被广泛用于治疗前列腺癌，因其在监测健康和环境状况及其过量使用时产生的荒谬的负面影响而迅速引起了医学科学领域的兴趣。这篇综述文章重点介绍了在开发基于混合和临床纳米样品的电化学传感器以同时电化学检测 FLT 方面取得的重要进展。文章重点介绍了用于检测 FLT 的不同电极的制造方法，如金刚石电极、丝网印刷碳电极 (SPCE)、玻璃碳电极 (GCE)、金电极 (AuE)、碳浆电极 (CPE) 和石墨铅笔电极。此外，还从未来的角度探讨了将基于纳米材料的不同类型电极传感器从实验室推向市场所面临的挑战。本综述讨论了有关不同类型电极的选择性报告，以探讨 2012 年至 2024 年期间 FLT 传感器的应用情况。本综述将成为研究人员的有用工具，为探索激动人心的新方向提供新视角和新思路。

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来源期刊

Microchemical Journal 化学-分析化学

CiteScore

8.70

自引率

8.30%

发文量

1131

审稿时长

1.9 months

期刊介绍： The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field. Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.