Superiority of 68 Ga-Trivehexin PET/CT Over 18 F-FDG PET/CT in the Evaluation of Lymph Nodes in Patients With Breast Cancer.

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-11-20 DOI:10.1097/RLU.0000000000005585
Halil Kömek, Yunus Güzel, İhsan Kaplan, Ece Eşsiz Yilmaz, Canan Can
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Abstract

Abstract: A patient with left upper quadrant breast cancer who had 18 F-FDG PET/CT imaging underwent 68 Ga-Trivehexin PET/CT. 68 Ga-Trivehexin PET/CT showed higher radiotracer accumulation in the primary tumor, left internal mammary lymph nodes, and axillary lymph nodes compared with 18 F-FDG PET/CT. However, Trivehexin uptake was not observed in FDG-positive lymph nodes in the mediastinum and left hilar region. Benign cytological findings were noted in the biopsy of the subcarinal lymph node. This case demonstrates that the use of 68 Ga-Trivehexin PET/CT in suspicious lymph nodes in areas difficult to biopsy in breast cancer cases can contribute to accurate staging.

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在评估乳腺癌患者淋巴结方面,68Ga-Trivehexin PET/CT 优于 18F-FDG PET/CT。
摘要:一名左上象限乳腺癌患者接受了 18F-FDG PET/CT 成像检查,并接受了 68Ga-Trivehexin PET/CT 检查。与 18F-FDG PET/CT 相比,68Ga-Trivehexin PET/CT 在原发肿瘤、左乳腺内淋巴结和腋窝淋巴结中显示出更高的放射性示踪剂积累。然而,在纵隔和左肺门的 FDG 阳性淋巴结中未观察到 Trivehexin 摄取。心包下淋巴结活检发现良性细胞学结果。本病例表明,在乳腺癌患者难以活检的可疑淋巴结部位使用 68Ga-Trivehexin PET/CT 有助于准确分期。
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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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