Microneedling Radiofrequency for Acne Vulgaris in Adolescents as a Promising Device-Based Treatment: A Clinical Case Series.

Giuseppe Lodi, Irene Fusco, Tiziano Zingoni, Giovanni Cannarozzo, Mario Sannino
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Abstract

Background: Acne vulgaris is a persistent inflammatory condition affecting the sebaceous unit, in whose pathophysiology the Propionibacterium acnes (P. acnes) play an important role, and that can have major psychological effects. Objective: The current study aims to investigate the safety and efficacy of an innovative fractional microneedle radiofrequency (RFMN) device for acne management in adolescents. Materials and Methods: A total of 21 Caucasian young patients with facial acne of all grades of severity underwent three treatment sessions spaced 15/30 days apart with an RFMN device. The Acne Radar Questionnaire was administered to all patients. The data were represented using Radar graph, and the sample population was distributed in quartiles. The first quartile, the second quartile, and the third quartile were calculated for all patient populations before and at 6 months follow-up (6 MFU). The evaluation of the severity of acne lesions was assessed by using the Global Acne Severity scale. Photographs of patients with acne were acquired with a digital camera before and at 6 MFU after the last treatment session. Results: The mean values of each item of the Acne Radar Questionnaire significantly (p < 0.001) improved for all patients treated. The analyses obtained by the quartiles showed that all variables improved after the treatment with the study device. The photographic images confirm the positive results and the improvement of acne lesions. No major side effects were observed. Conclusions: The study system appears to be an effective and safe treatment choice for patients with inflammatory active acne and acne scarring.

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微针射频治疗青少年痤疮是一种很有前景的基于设备的治疗方法:临床病例系列。
背景:寻常痤疮是一种影响皮脂腺单位的持续性炎症,痤疮丙酸杆菌(P. acnes)在其病理生理学中起着重要作用,并可能对心理产生重大影响。研究目的本研究旨在探讨创新型点阵微针射频(RFMN)设备治疗青少年痤疮的安全性和有效性。材料与方法:共有 21 名患有各种严重程度面部痤疮的白种人青少年患者接受了 RFMN 设备的三次治疗,每次间隔 15/30 天。对所有患者进行了痤疮雷达问卷调查。数据用雷达图表示,样本人群按四分位数分布。在随访前和随访 6 个月(6 MFU)时,计算所有患者的第一四分位数、第二四分位数和第三四分位数。对痤疮皮损严重程度的评估采用全球痤疮严重程度量表。用数码相机拍摄痤疮患者在最后一次治疗前和治疗后 6 个月时的照片。结果显示所有接受治疗的患者的痤疮雷达问卷各项目平均值均有明显改善(p < 0.001)。按四分法进行的分析表明,在使用研究设备进行治疗后,所有变量都有所改善。照片图像证实了积极的效果和痤疮皮损的改善。没有观察到严重的副作用。结论该研究系统似乎是炎症性活动性痤疮和痤疮瘢痕患者的一种有效而安全的治疗选择。
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4.10
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期刊介绍: Photobiomodulation, Photomedicine, and Laser Surgery Editor-in-Chief: Michael R Hamblin, PhD Co-Editor-in-Chief: Heidi Abrahamse, PhD
期刊最新文献
Photodynamic Therapy or Palliative Resection Versus Biliary Stenting for Advanced Cholangiocarcinoma: A Network Meta-Analysis. Microneedling Radiofrequency for Acne Vulgaris in Adolescents as a Promising Device-Based Treatment: A Clinical Case Series. Antimicrobial Photodynamic Therapy in the Treatment of Diabetic Foot Ulcer: A Scoping Review. "Five-Step" Vaporization of the Prostate Using 180-W XPS Greenlight Laser in Patients with Benign Prostatic Hyperplasia of Large Volume: Improved Efficacy and Safety. Effects of Laser Acupuncture on Metabolic Functions of Sedentary People: A Double-Blind Randomized Clinical Trial.
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