Prevalence of Trypanosoma cruzi Infection in Solid Organ Transplant Recipients: A Neglected Disease in America.

IF 3.8 4区 医学 Q2 IMMUNOLOGY Open Forum Infectious Diseases Pub Date : 2024-11-08 eCollection Date: 2024-12-01 DOI:10.1093/ofid/ofae650
German A Contreras, George Golovko
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Abstract

This study investigates the prevalence of Trypanosoma cruzi infection among solid organ transplant recipients in the United States from 2019 to 2023 before transplantation. Utilizing data from a large multicenter network, we identified a rising seroprevalence of 4.8% from 1523 solid organ transplant recipients at the time of the evaluation for transplantation, particularly among lung and heart transplant recipients. The findings highlight the need for improved screening protocols to address this neglected tropical disease in transplant populations.

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实体器官移植受者中的克鲁兹锥虫感染流行率:美国被忽视的疾病。
本研究调查了2019年至2023年美国实体器官移植受者在移植前感染克氏锥虫的流行情况。利用一个大型多中心网络的数据,我们从1523名实体器官移植受者中发现,在进行移植评估时,血清流行率上升了4.8%,尤其是在肺移植和心脏移植受者中。这些发现强调了改进筛查方案的必要性,以应对移植人群中这种被忽视的热带疾病。
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来源期刊
Open Forum Infectious Diseases
Open Forum Infectious Diseases Medicine-Neurology (clinical)
CiteScore
6.70
自引率
4.80%
发文量
630
审稿时长
9 weeks
期刊介绍: Open Forum Infectious Diseases provides a global forum for the publication of clinical, translational, and basic research findings in a fully open access, online journal environment. The journal reflects the broad diversity of the field of infectious diseases, and focuses on the intersection of biomedical science and clinical practice, with a particular emphasis on knowledge that holds the potential to improve patient care in populations around the world. Fully peer-reviewed, OFID supports the international community of infectious diseases experts by providing a venue for articles that further the understanding of all aspects of infectious diseases.
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