Iridoid glycosides from the flowers of Gardenia jasminoides: Isolation, characterization, and antioxidant potential

IF 2.5 3区 医学 Q3 CHEMISTRY, MEDICINAL Fitoterapia Pub Date : 2024-11-26 DOI:10.1016/j.fitote.2024.106316
Wei Li , Huiyu Li , Qingsen Shao , Xueci Liang , Qiugui Zhou , Yun Tang
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Abstract

Four new iridoids elucidated as jasmigeniposide C (1), jasmigeniposide D (2), jasmigeniposide E (3), and jasmigeniposide F (4), along with six known iridoids (510) were isolated from the flowers of Gardenia jasminoides. Their structures were determined on the basis of spectroscopic analyses and chemical reactions. The antioxidant activities of these compounds were preliminarily evaluated by DPPH radical scavenging assay. The results revealed that compounds 15 exhibited some antioxidant activity. Notably, compound 2 displayed the most potent antioxidant activity among the tested compounds.

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栀子花环烯醚萜苷的分离、表征及抗氧化活性研究。
从栀子花中分离到4个新的环烯醚萜类化合物,分别为栀子苷C(1)、栀子苷D(2)、栀子苷E(3)和栀子苷F(4),以及6个已知的环烯醚萜类化合物(5-10)。通过光谱分析和化学反应确定了它们的结构。通过DPPH自由基清除实验初步评价了这些化合物的抗氧化活性。结果表明,化合物1 ~ 5具有一定的抗氧化活性。其中化合物2的抗氧化活性最强。
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来源期刊
Fitoterapia
Fitoterapia 医学-药学
CiteScore
5.80
自引率
2.90%
发文量
198
审稿时长
1.5 months
期刊介绍: Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas: 1. Characterization of active ingredients of medicinal plants 2. Development of standardization method for bioactive plant extracts and natural products 3. Identification of bioactivity in plant extracts 4. Identification of targets and mechanism of activity of plant extracts 5. Production and genomic characterization of medicinal plants biomass 6. Chemistry and biochemistry of bioactive natural products of plant origin 7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.
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