Outbreak of paediatric myocarditis associated with parvovirus B19 infection in Italy, January to October 2024.

IF 7.8 2区 医学 Q1 INFECTIOUS DISEASES Eurosurveillance Pub Date : 2024-11-01 DOI:10.2807/1560-7917.ES.2024.29.48.2400746
Marco Poeta, Cristina Moracas, Francesca Ippolita Calò Carducci, Claudio Cafagno, Danilo Buonsenso, Marco Maglione, Sofia Sgubbi, Cecilia Liberati, Elisabetta Venturini, Giuseppe Limongelli, Felice Nunziata, Laura Petrarca, Claudia Mandato, Claudia Colomba, Alfredo Guarino
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Abstract

Acute myocarditis has risen among paediatric patients in Italy, with 65 clinically suspected cases reported by 12 centres in 2024, 32 linked to parvovirus B19 (B19V) infection. In 11 cases, B19V was not ruled out despite a concurrent European outbreak. Twenty-nine children required intensive care; eight fatalities occurred. While effective for both severe B19V infection and myocarditis, intravenous immunoglobulins were given in only one-third of cases. These findings highlight the need for timely diagnosis, stronger surveillance, and standardised treatment protocols.

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2024年1月至10月意大利与细小病毒B19感染相关的小儿心肌炎暴发
意大利儿科急性心肌炎患者有所增加,2024年12个中心报告了65例临床疑似病例,其中32例与细小病毒B19 (B19V)感染有关。在11例病例中,尽管欧洲同时爆发了B19V,但仍未排除。29名儿童需要重症监护;造成8人死亡。虽然对严重B19V感染和心肌炎都有效,但静脉注射免疫球蛋白仅对三分之一的病例有效。这些发现强调了及时诊断、加强监测和标准化治疗方案的必要性。
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来源期刊
Eurosurveillance
Eurosurveillance INFECTIOUS DISEASES-
CiteScore
32.70
自引率
2.10%
发文量
430
审稿时长
3-8 weeks
期刊介绍: Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.
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