Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round
{"title":"Draft genome of a human gut-derived <i>Blautia</i> sp. that ameliorates colitis and colitis-associated sociability deficits in mice.","authors":"Michaela A Murphy, D Garrett Brown, Rickesha S Bell, Allison M Weis, Logan A Barrios, W Zac Stephens, June L Round","doi":"10.1128/mra.00726-24","DOIUrl":null,"url":null,"abstract":"<p><p><i>Blautia</i> is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different <i>Blautia</i> strains can impact host health is poorly understood. We present a <i>Blautia</i> sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.</p>","PeriodicalId":18654,"journal":{"name":"Microbiology Resource Announcements","volume":" ","pages":"e0072624"},"PeriodicalIF":0.7000,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737165/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbiology Resource Announcements","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1128/mra.00726-24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/29 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Blautia is a genus of anaerobic, gram-positive bacteria commonly found in mammalian gastrointestinal tracts. Yet, how variations among different Blautia strains can impact host health is poorly understood. We present a Blautia sp. genome isolated from human feces whose supplementation to mice can ameliorate colitis severity and associated sociability deficits.