Rh(II)‐Catalyzed Tandem Reaction of 2‐Trimethylsiloxy‐pyridine and α‐Trifluoromethyl Diazomethane: An Approach to Tetrasubstituted gem‐Difluoro Olefins
Guang‐Hui Li , Xin‐Yu Huang , Jun‐Xi Lv , Xue‐Di Zhao , Prof. Dr. Shengchao Yang , Prof. Dr. Lu Liu
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引用次数: 0
Abstract
Herein, we describe a Rh2(OAc)4‐catalyzed reaction of 2‐trimethylsiloxy‐pyridine and fluorinated diazomethanes, which provides an effective and straightforward approach to the synthesis of 2‐oxopyridinyl tetrasubstituted gem‐difluoro olefins. This protocol features good functional group compatibility, mild reaction conditions, good yield, and readily available substrates.
期刊介绍：
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.
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