Jinglin Ma , Fengxi Li , Hanqing Xie , Chunyu Wang , Wenhan Shi , Lei Wang , Peng Chen , Zhi Wang
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引用次数: 0
Abstract
A lipase-catalyzed, mild and environmentally friendly synthesis of polyhydroxyalkyl pyrroles from various unprotected sugars, benzoylacetonitriles and NH4OAc/benzylamine in water was reported for the first time in this work. Moreover, the synthetic potentiality of this enzymatic method was demonstrated by easy isolation of the final products using filtration. This green synthesis and purification approach not only enriches the strategies for synthesis of polyhydroxyalkyl pyrroles, but also expands the application of lipase in organic synthesis.
期刊介绍：
Molecular Catalysis publishes full papers that are original, rigorous, and scholarly contributions examining the molecular and atomic aspects of catalytic activation and reaction mechanisms. The fields covered are:
Heterogeneous catalysis including immobilized molecular catalysts
Homogeneous catalysis including organocatalysis, organometallic catalysis and biocatalysis
Photo- and electrochemistry
Theoretical aspects of catalysis analyzed by computational methods
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