Impaired adipocyte-mediated regulation of fibroblasts in inflammatory arthritis

IF 29.4 1区 医学 Q1 RHEUMATOLOGY Nature Reviews Rheumatology Pub Date : 2024-12-03 DOI:10.1038/s41584-024-01202-9
Holly Webster
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引用次数: 0

Abstract

A study reports that adipocytes can regulate the metabolism of fibroblasts in the healthy synovium via cortisol, but in inflammatory arthritis adiposity is lost and fibroblasts become pathogenic.
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炎性关节炎中脂肪细胞介导的成纤维细胞调节受损
一项研究报道,脂肪细胞可以通过皮质醇调节健康滑膜中成纤维细胞的代谢,但在炎症性关节炎中,脂肪丢失,成纤维细胞成为致病性的。
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来源期刊
Nature Reviews Rheumatology
Nature Reviews Rheumatology 医学-风湿病学
CiteScore
29.90
自引率
0.90%
发文量
137
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.
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