{"title":"Natural Products Driven Medicinal Chemistry","authors":"Sandip B. Bharate, Craig W. Lindsley","doi":"10.1021/acs.jmedchem.4c02736","DOIUrl":null,"url":null,"abstract":"Figure 1. Classical NPs that led to the discovery of drug molecules for therapeutic use. The year of discovery and the name of the researcher who isolated it for the first time are also mentioned. Figure 2. Anticancer leads identified through NP-driven medicinal chemistry. Figure 3. Leads for CNS diseases identified through NP-driven medicinal chemistry. Figure 4. Leads for infectious diseases identified through NP-driven medicinal chemistry. Figure 5. Anti-inflammatory lead compounds identified through NP-driven medicinal chemistry. Figure 6. Other lead compounds identified through NP-driven medicinal chemistry. Figure 7. Hits/leads identified through screening of NP-based libraries. Figure 8. Opportunities in NP-based drug discovery. This article references 18 other publications. This article has not yet been cited by other publications.","PeriodicalId":46,"journal":{"name":"Journal of Medicinal Chemistry","volume":"64 1","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medicinal Chemistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1021/acs.jmedchem.4c02736","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Figure 1. Classical NPs that led to the discovery of drug molecules for therapeutic use. The year of discovery and the name of the researcher who isolated it for the first time are also mentioned. Figure 2. Anticancer leads identified through NP-driven medicinal chemistry. Figure 3. Leads for CNS diseases identified through NP-driven medicinal chemistry. Figure 4. Leads for infectious diseases identified through NP-driven medicinal chemistry. Figure 5. Anti-inflammatory lead compounds identified through NP-driven medicinal chemistry. Figure 6. Other lead compounds identified through NP-driven medicinal chemistry. Figure 7. Hits/leads identified through screening of NP-based libraries. Figure 8. Opportunities in NP-based drug discovery. This article references 18 other publications. This article has not yet been cited by other publications.
期刊介绍：
The Journal of Medicinal Chemistry is a prestigious biweekly peer-reviewed publication that focuses on the multifaceted field of medicinal chemistry. Since its inception in 1959 as the Journal of Medicinal and Pharmaceutical Chemistry, it has evolved to become a cornerstone in the dissemination of research findings related to the design, synthesis, and development of therapeutic agents.
The Journal of Medicinal Chemistry is recognized for its significant impact in the scientific community, as evidenced by its 2022 impact factor of 7.3. This metric reflects the journal's influence and the importance of its content in shaping the future of drug discovery and development. The journal serves as a vital resource for chemists, pharmacologists, and other researchers interested in the molecular mechanisms of drug action and the optimization of therapeutic compounds.
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