Dual organ transplantation: Pancreas and Liver in the kidney axis.

IF 2.2 3区 医学 Q3 PERIPHERAL VASCULAR DISEASE Current Opinion in Nephrology and Hypertension Pub Date : 2025-03-01 Epub Date: 2024-12-06 DOI:10.1097/MNH.0000000000001049
Manal E Alotaibi, Sam Kant
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Abstract

Purpose of review: This article explores the benefits and challenges of dual organ transplants.

Recent findings: Simultaneous liver-kidney transplant has become a valuable option for patients with both liver and kidney failure, especially since the introduction of clearer eligibility guidelines in 2017. When done for the appropriate candidate, it can significantly improve survival and quality of life. Similarly, simultaneous pancreas-kidney transplantation provides significant advantages for patients with diabetes-related kidney failure by addressing both glycemic control and kidney function, with significant improvement in diabetes associated complications and survival.

Summary: While these procedures are complex, they offer promising solutions for managing difficult multiorgan conditions. Ongoing research and personalized patient care will be key to maximizing their benefits.

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双器官移植:胰腺和肝脏在肾轴。
综述目的:本文探讨双器官移植的益处和挑战。最近的研究结果:同步肝肾移植已成为肝肾衰竭患者的一个有价值的选择,特别是自2017年引入更明确的资格指南以来。当对合适的候选者进行治疗时,它可以显著提高生存率和生活质量。同样,同时胰肾移植通过解决血糖控制和肾功能问题,为糖尿病相关性肾衰竭患者提供了显著的优势,显著改善了糖尿病相关并发症和生存率。虽然这些手术很复杂,但它们为治疗困难的多器官疾病提供了有希望的解决方案。正在进行的研究和个性化的病人护理将是最大限度地发挥其效益的关键。
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来源期刊
Current Opinion in Nephrology and Hypertension
Current Opinion in Nephrology and Hypertension 医学-泌尿学与肾脏学
CiteScore
5.70
自引率
6.20%
发文量
132
审稿时长
6-12 weeks
期刊介绍: A reader-friendly resource, Current Opinion in Nephrology and Hypertension provides an up-to-date account of the most important advances in the field of nephrology and hypertension. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including pathophysiology of hypertension, circulation and hemodynamics, and clinical nephrology. Current Opinion in Nephrology and Hypertension is an indispensable journal for the busy clinician, researcher or student.
期刊最新文献
Built environment and chronic kidney disease: current state and future directions. Dual organ transplantation: Pancreas and Liver in the kidney axis. Effect of the allelic background on the phenotype of primary hyperoxaluria type I. Home dialysis: there's no place like home. The kidney under heat stress: a vulnerable state.
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