Zhanrong Zhou, Xin Wang, Hongqing Wang, Hongjie Shao, Junhua Sun, Ruoyun Chen, Jie Kang
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引用次数: 0
Abstract
Seven benzylisoquinoline alkaloids, including three new (1-3) and four known compounds (4-7), were isolated from the embryo of Nelumbo nucifera (Plumula Nelumbinis). Their structures were elucidated by UV, IR, HRESIMS, 1D and 2D NMR, and ECD spectra, as well as optical rotations. All compounds were tested for the antioxidant activity. Compounds 1-7 prevented Fe2+ induced lipid peroxidation in mouse liver microsomes, with the inhibitory rates of 76.1, 75.7, 60.0, 82.9, 75.5, 83.8 and 85.3 %, respectively.
期刊介绍：
Fitoterapia is a Journal dedicated to medicinal plants and to bioactive natural products of plant origin. It publishes original contributions in seven major areas:
1. Characterization of active ingredients of medicinal plants
2. Development of standardization method for bioactive plant extracts and natural products
3. Identification of bioactivity in plant extracts
4. Identification of targets and mechanism of activity of plant extracts
5. Production and genomic characterization of medicinal plants biomass
6. Chemistry and biochemistry of bioactive natural products of plant origin
7. Critical reviews of the historical, clinical and legal status of medicinal plants, and accounts on topical issues.
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