A Rare Case of Granular Cell Tumor of the Anus

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL Clinical Case Reports Pub Date : 2024-12-05 DOI:10.1002/ccr3.9688
C. H. Mehta, E. J. Kantzler, M. Suzuki, M. D. Honaker
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Abstract

Granular cell tumors (GCTs) are uncommon soft tissue neoplasms derived from Schwann cells that can arise from various regions of the body. The majority originate from the head and neck. They are rarely encountered in the gastrointestinal tract and even more rarely in the anorectal region. There is a paucity of literature with only a few case reports of GCT of the anus. We describe a 36-year-old African American male with a long-standing history of human immunodeficiency virus (HIV) infection, multiple perianal abscess and associated fistulas, and an ulcerated perianal lesion that revealed an anal GCT who was treated with excision and surveillance. Given that GCTs in the perianal region are extremely rare, a high index of suspicion of GCT of the anus is critical when patients present with anal masses, ulcers, or abscesses given the extremely poor prognosis of malignant GCTs.

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肛门颗粒细胞瘤1例。
颗粒细胞瘤(gct)是源于雪旺细胞的罕见软组织肿瘤,可出现在身体的各个部位。大多数来自头部和颈部。它们很少发生在胃肠道,更很少发生在肛肠区。文献资料的缺乏,只有少数病例报告的肛门GCT。我们描述了一位36岁的非裔美国男性,长期感染人类免疫缺陷病毒(HIV),多发性肛周脓肿和相关瘘管,以及一个溃疡的肛周病变,显示肛门GCT,他接受了切除和监测治疗。鉴于肛周区域的GCT极为罕见,当患者出现肛门肿块、溃疡或脓肿时,高度怀疑肛门GCT是至关重要的,因为恶性GCT预后极差。
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来源期刊
Clinical Case Reports
Clinical Case Reports MEDICINE, GENERAL & INTERNAL-
自引率
14.30%
发文量
1268
审稿时长
13 weeks
期刊介绍: Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).
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