Precipitate, preterm labor in acute organophosphate poisoning in pregnancy: a case report.

IF 1.7 Q2 MEDICINE, GENERAL & INTERNAL Annals of Medicine and Surgery Pub Date : 2024-11-14 eCollection Date: 2024-12-01 DOI:10.1097/MS9.0000000000002721

Rosy Shah, Amrit Pokhrel, Anil Shrestha, Saroj Shrestha, Amrita Sah, Raj Shah

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Abstract

Introduction: Acute organophosphorus poisoning (AOPP) during pregnancy is uncommon. When complicated by preterm labor, it presents therapeutic dilemmas due to the lack of established guidelines.

Case presentation: The authors describe a case of a 19-year-old primigravida at 33 weeks of gestation with AOPP. During her treatment, she unexpectedly experienced preterm, precipitate labor, resulting in the delivery of a live, healthy baby.

Discussion: Late-pregnancy exposure to organophosphates may trigger preterm labor through receptor hyperstimulation from excess acetylcholine, causing premature contractions. Atropine, progesterone, and magnesium sulfate may help manage these effects.

Conclusion: This case underscores the importance of vigilance and frequent clinical examinations in patients with AOPP to identify subtle early signs of potential complications.

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妊娠期急性有机磷中毒所致沉淀、早产1例。

妊娠期急性有机磷中毒（AOPP）并不常见。当早产并发症时，由于缺乏既定的指导方针，它提出了治疗难题。病例介绍：作者描述了一个19岁的初产妇在33周妊娠与AOPP的情况。在她的治疗期间，她意外地经历了早产，早产，导致一个健康的婴儿出生。讨论：妊娠后期暴露于有机磷可通过过量乙酰胆碱对受体的过度刺激引发早产，引起宫缩过早。阿托品、黄体酮和硫酸镁可能有助于控制这些影响。结论：本病例强调了警惕和频繁的临床检查对AOPP患者的重要性，以发现潜在并发症的细微早期迹象。

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Annals of Medicine and Surgery MEDICINE, GENERAL & INTERNAL-

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1665