Adiposity is associated with a higher number of thyroid nodules and worse FNA outcomes.

IF 3.5 2区医学 Q2 ENDOCRINOLOGY & METABOLISM European Thyroid Journal Pub Date : 2024-12-01 DOI:10.1530/ETJ-24-0176

Elpida Demetriou, Aliki Economides, Maria Fokou, Demetris Lamnisos, Stavroula A Paschou, Panagiotis Papageorgis, Panayiotis A Economides

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引用次数: 0

Abstract

Background: Adiposity may be associated with thyroid nodularity. However, its impact on the number of nodules and the risk of malignancy is unclear.

Aim: To evaluate the impact of adiposity on thyroid nodules using Body Mass Index (BMI), ultrasonographic (US) and cytological data.

Methods: A retrospective cohort study of 310 patients with thyroid nodules was performed. Patients were categorized based on their BMI, and grayscale US data and fine-needle aspiration (FNA) cytology results were evaluated.

Results: Patients with BMI ≥25 Kg/ m² were found to have a higher number of thyroid nodules compared to those with BMI <25 Kg/ m² (4.25 ±2.42 vs. 3.66 ± 1.93) (P value=0.05). Patients with BMI ≥25 Kg/ m² had more suspicious and malignant cytology than those with BMI <25 Kg/ m² (P value = 0.029). Patients with BMI ≥25 Kg/m² had more nodules with intermediate and high suspicion sonographic patterns. However, this did not reach statistical significance.

Conclusion: Overweight and obese patients have a trend for more thyroid nodules and have a higher risk of being diagnosed with thyroid malignancy.

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来源期刊

European Thyroid Journal Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

6.70

自引率

2.10%

发文量

156

期刊介绍： The ''European Thyroid Journal'' publishes papers reporting original research in basic, translational and clinical thyroidology. Original contributions cover all aspects of the field, from molecular and cellular biology to immunology and biochemistry, from physiology to pathology, and from pediatric to adult thyroid diseases with a special focus on thyroid cancer. Readers also benefit from reviews by noted experts, which highlight especially active areas of current research. The journal will further publish formal guidelines in the field, produced and endorsed by the European Thyroid Association.