Cluster of extensively drug-resistant Shigella sonnei carrying blaCTX-M-15 in Los Angeles, California, 2023 to 2024

IF 2.4 3区 医学 Q2 INFECTIOUS DISEASES American journal of infection control Pub Date : 2025-04-01 Epub Date: 2024-12-10 DOI:10.1016/j.ajic.2024.12.005
JR Caldera PhD, D(ABMM) , Bennett Shaw , Daniel Z. Uslan MD, MBA, FIDSA, FSHEA , Shangxin Yang PhD, D(ABMM)
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Abstract

We describe 3 cases of extensively drug-resistant Shigella sonnei infections among men who have sex with men in Los Angeles, CA. Using whole-genome sequencing, we determined that they are highly genetically related, exhibit similar antimicrobial resistomes, and appear to be distinct from other circulating strains. These cases highlight the rapid expansion of extensively drug-resistant Shigella in the United States and the urgent need for appropriate detection and management.
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2023-2024年加州洛杉矶携带blaCTX-M-15的广泛耐药sonnei志贺菌群
我们描述了加利福尼亚州洛杉矶男男性行为者(MSM)中3例广泛耐药(XDR)索尼氏志贺氏菌感染病例。使用全基因组测序,我们确定它们具有高度遗传相关性,表现出相似的抗微生物耐药性,并且似乎与其他流行菌株不同。这些病例突出了广泛耐药志贺氏菌在美国的迅速蔓延,以及对适当检测和管理的迫切需要。
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来源期刊
CiteScore
7.40
自引率
4.10%
发文量
479
审稿时长
24 days
期刊介绍: AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)
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