Quilomicronemia multifactorial: claves para la detección de las formas severas

IF 1.9 Q3 PERIPHERAL VASCULAR DISEASE Clinica e Investigacion en Arteriosclerosis Pub Date : 2024-12-01 DOI:10.1016/j.arteri.2024.11.003
Ovidio Muñiz-Grijalvo , Agustín Blanco Echevarría , María José Ariza Corbo , José Luis Díaz-Díaz
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Abstract

Multifactorial chylomicronemia associated with multiple comorbidities, drugs and habits is much more common than familial chylomicronemia, an autosomal recessive disease that can be considered as “rare disease”. Like the rest of hypertriglyceridemias, chylomicronemias could be classified as primary or monogenic and secondary in which, on the basis of polygenic predisposition, there is concomitant exposure to multiple triggering factors. In this brief revision, we will review its causes and management as well as the keys to its differential diagnosis of the Multifactorial Chylomicronemia.
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多因素乳糜微粒血症:检测严重形式的关键。
与家族性乳糜微粒血症相比,与多种并发症、药物和习惯相关的多因素乳糜微粒血症要常见得多,而家族性乳糜微粒血症是一种常染色体隐性遗传病,可被视为 "罕见病"。与其他高甘油三酯血症一样,乳糜泻也可分为原发性或单基因型和继发性,其中继发性乳糜泻是在多基因易感性的基础上,同时暴露于多种诱发因素。在这篇简短的修订中,我们将回顾其病因和治疗方法,以及多因素乳糜微粒血症鉴别诊断的关键。
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来源期刊
Clinica e Investigacion en Arteriosclerosis
Clinica e Investigacion en Arteriosclerosis PERIPHERAL VASCULAR DISEASE-
CiteScore
3.20
自引率
6.20%
发文量
44
审稿时长
40 days
期刊介绍: La publicación idónea para acceder tanto a los últimos originales de investigación como a formación médica continuada sobre la arteriosclerosis y su etiología, epidemiología, fisiopatología, diagnóstico y tratamiento. Además, es la publicación oficial de la Sociedad Española de Arteriosclerosis.
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