Impact of phenylephrine-induced Hering's response on Müller's muscle-conjunctival resection outcomes.

IF 0.8 Q4 OPHTHALMOLOGY Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery Pub Date : 2025-06-01 Epub Date: 2024-12-16 DOI:10.1080/01676830.2024.2435928

Niloufar Bineshfar, Leo Meller, Benjamin I Meyer, Wendy W Lee

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引用次数: 0

Abstract

Purpose: To evaluate the impact of preoperative phenylephrine (PE)-induced Hering's response on postoperative outcomes in patients undergoing unilateral Müller's muscle-conjunctival resection (MMCR) for blepharoptosis correction.

Methods: Sixty-five consecutive patients (65 eyes) undergoing unilateral MMCR between January 2016 and December 2023 were included in this retrospective single-surgeon study. The main outcome measure was the margin-reflex distance 1 (MRD1) at postoperative month 1 visit. Logistic regression analysis was conducted to identify factors influencing postoperative Hering's response.

Results: A preoperative post-PE Hering's response was observed in 40.0% of patients. At 1 week and 1 month postoperatively, Hering's response was recorded in 20.0% and 21.5% of cases, respectively. Regression analysis revealed a significant correlation between preoperative post-PE Hering's and post-MMCR Hering's response at postoperative month 1 visit (crude odds ratio (OR): 8.80, p = .003; adjusted OR: 30.43, p = .002).

Conclusion: Preoperative post-PE Hering's response is a significant predictor of postoperative Hering's response in unilateral MMCR.

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苯肾上腺素诱发的赫林氏反应对 Müller 肌肉结膜切除术结果的影响。

目的：评估术前苯肾上腺素（PE）诱导的赫林氏反应对接受单侧缪勒肌-结膜切除术（MMCR）矫正眼睑外翻患者术后效果的影响：这项回顾性单外科医师研究纳入了 2016 年 1 月至 2023 年 12 月间接受单侧 Müller 肌肉-结膜切除术的 65 例连续患者（65 只眼）。主要结果指标是术后第1个月访视时的边缘-反射距离1（MRD1）。为确定影响术后赫林反应的因素，进行了逻辑回归分析：结果：40.0%的患者术前观察到了PE术后赫林氏反应。术后 1 周和 1 个月，分别有 20.0% 和 21.5% 的病例出现赫林氏反应。回归分析显示，在术后第 1 个月就诊时，术前 PE 后赫林氏反应与术后 MMCR 后赫林氏反应之间存在明显的相关性（粗略赔率 (OR)：8.80，p = .003；调整赔率：30.43，p = .00）：结论：结论：在单侧 MMCR 中，术前 PE 后 Hering's 反应是术后 Hering's 反应的重要预测因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Orbit-The International Journal on Orbital Disorders-Oculoplastic and Lacrimal Surgery OPHTHALMOLOGY-

CiteScore

2.40

自引率

9.10%

发文量

136

期刊介绍： Orbit is the international medium covering developments and results from the variety of medical disciplines that overlap and converge in the field of orbital disorders: ophthalmology, otolaryngology, reconstructive and maxillofacial surgery, medicine and endocrinology, radiology, radiotherapy and oncology, neurology, neuroophthalmology and neurosurgery, pathology and immunology, haematology.