At a glance

IF 3.7 2区 医学 Q1 OPHTHALMOLOGY British Journal of Ophthalmology Pub Date : 2025-01-01 DOI:10.1136/bjo-2024-326873
Frank Larkin
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Abstract

A national corneal transplant registry analysis of 11,516 endothelial keratoplasty procedures found clear evidence that increasing surgeon experience in that procedure was associated with longer two-year transplant survival. This strongly supports best feasible arrangements for surgeon training and mentoring at the introduction of new procedures. This trial examined the usefulness of short-term 1% topical ciclosporin in cases of acute Stevens-Johnson syndrome (SJS). Additional therapy with 1% ciclosporin was not efficacious over standard therapy in stabilising the ocular surface in cases of acute SJS. Twenty years following an equivalent study, contact lens wear remained the leading risk factor for bacterial keratitis. A majority of Gram-negative bacteria were found, with a marked increase in Moraxella keratitis and a low rate of antibacterial drug resistance. Based on their proposed keratitis grading system, the authors' study provides a reportedly safe, evidence-based management protocol for patients with contact lens associated keratitis (CLAK). This should improve resource allocation and at a time of increasing demand for eye care services by reducing unnecessary patient visits. In a real-world registry, most non-infectious non-anterior uveitis cases were found to require immunosuppression with biologic and/or …
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一目了然
一项对11516例内皮角膜移植术进行的全国角膜移植登记分析发现,有明确证据表明,增加该手术的外科医生经验与较长的两年移植生存期相关。这有力地支持了在引入新手术时对外科医生进行培训和指导的最佳可行安排。本试验探讨了1%短期局部环孢素治疗急性史蒂文斯-约翰逊综合征(SJS)的有效性。在稳定急性SJS病例的眼表方面,1%环孢素的额外治疗并不比标准治疗有效。经过20年的同等研究,隐形眼镜佩戴仍然是细菌性角膜炎的主要危险因素。革兰氏阴性菌居多,角膜炎莫拉菌明显增多,抗菌药物耐药率低。基于他们提出的角膜炎分级系统,作者的研究为隐形眼镜相关性角膜炎(CLAK)患者提供了一种安全的、基于证据的管理方案。这将通过减少不必要的患者就诊,改善资源分配,并在对眼科保健服务需求不断增加的时候。在现实世界的登记中,大多数非感染性非前路葡萄膜炎病例需要免疫抑制与生物和/或…
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来源期刊
CiteScore
10.30
自引率
2.40%
发文量
213
审稿时长
3-6 weeks
期刊介绍: The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. It also provides major reviews and also publishes manuscripts covering regional issues in a global context.
期刊最新文献
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