Rücktitelbild: Unlocking of Hidden Mesopores for Enzyme Encapsulation by Dynamic Linkers in Stable Metal-Organic Frameworks (Angew. Chem. 51/2024)

Abstract

Dynamic boroxine linkers were incorporated into the mesoporous metal–organic framework (MOF) PCN-333, which creates defects and expands pore sizes, enabling the encapsulation of enzymes larger than the intrinsic MOF pores. As reported by Xing Zhang, Shuai Yuan et al in their Research Article (e202409951), this strategy facilitates the immobilization of glycoenzymes for synthesizing complex oligosaccharides and polysaccharides, demonstrating both high activity and enhanced enzyme stability.