Therapeutic Potential of Emodin: A Mini-Review of Its Anti-Biofilm and Antimicrobial Effects.

Samane Teymouri, Maryam Pourhajibagher, Abbas Bahador
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Abstract

The resistance of biofilms to antimicrobial agents presents numerous challenges. The formation of biofilms leads to enhanced resistance to adverse environmental condi-tions, as well as to antimicrobial agents. Natural compounds have been of interest as po-tential therapeutic agents. Emodin, a natural anthraquinone compound, has recently at-tracted attention for its potential as a broad-spectrum antimicrobial agent. This ability could potentially help combat biofilm-associated infections and enhance the effectiveness of an-timicrobial therapies. This review was carried out to evaluate the effects of emodin on mi-crobial biofilms, determine its effectiveness in inhibiting and reducing biofilm formation, eradicate biofilms, and examine its antimicrobial effects. Our study shows that the use of emodin as an additional therapeutic agent in combating microbial biofilms holds consider-able promise. As researchers continue to investigate how emodin interacts with microbial biofilms, there is excitement about the potential applications of this natural compound in addressing biofilm-related issues. However, it is suggested to pay more attention to evalu-ating the effects of emodin on microbial biofilms in future studies.

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大黄素的治疗潜力:其抗生物膜和抗菌作用的综述。
生物膜对抗菌剂的耐药性提出了许多挑战。生物膜的形成导致对不利环境条件的抵抗力增强,以及对抗菌剂的抵抗力。天然化合物作为潜在的治疗剂已引起人们的兴趣。大黄素是一种天然的蒽醌类化合物,近年来因其作为广谱抗菌剂的潜力而受到关注。这种能力可能有助于对抗生物膜相关感染,并提高抗微生物疗法的有效性。本文综述了大黄素对微生物生物膜的影响,确定了其抑制和减少生物膜形成、根除生物膜的有效性,并考察了其抗菌作用。我们的研究表明,使用大黄素作为对抗微生物生物膜的额外治疗剂具有相当大的前景。随着研究人员继续研究大黄素如何与微生物生物膜相互作用,人们对这种天然化合物在解决生物膜相关问题方面的潜在应用感到兴奋。但是,建议在未来的研究中更多地关注大黄素对微生物生物膜的影响。
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