Evaluation of postoperative intracranial pressure in patients with radiological diagnosis of idiopathic intracranial hypertension

IF 1.8 4区 医学 Q2 OTORHINOLARYNGOLOGY American Journal of Otolaryngology Pub Date : 2025-01-01 DOI:10.1016/j.amjoto.2024.104542
Valeria Barcia Castilla , Pedro Mino Vianna , Rodrigo Aragão Torres , Fabiolla Maria Martins Costa , Luziana de Lima Ramalho , Débora de Carvalho Garcez , Rogerio Pezato , Beatriz Sarno Ramos , José Marcelo Ferreira Bezerra , Miguel Soares Tepedino
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Abstract

Objective

This study aimed to assess postoperative intracranial pressure in patients with clinical and/or radiological features of idiopathic intracranial hypertension (IIH) undergoing endoscopic endonasal surgery for primary cerebrospinal fluid (CSF) leak repair.

Methods

Data was prospectively collected from 9 patients diagnosed with CSF nasal leaks who underwent corrective endonasal surgery between January 1, 2021, and October 31, 2022. Postoperative intracranial pressure was measured via lumbar puncture at least one month after surgery. Preoperative and postoperative MRI scans were compared to evaluate changes.

Results

Postoperative lumbar puncture revealed elevated intracranial pressure in 67 % of patients, and 100 % showed persistent signs of intracranial hypertension on MRI.

Conclusion

Managing elevated intracranial pressure in patients with CSF nasal leaks should be prioritized alongside surgical correction. Consideration of permanent peritoneal shunt or pharmacological treatment may be necessary for patients with classic IIH phenotype. Longitudinal studies are essential for further understanding long-term outcomes.
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影像学诊断特发性颅内高压患者术后颅内压的评价。
目的:本研究旨在评估具有临床和/或影像学特征的特发性颅内高压(IIH)患者接受内镜下鼻内手术进行原发性脑脊液(CSF)泄漏修复的术后颅内压。方法:前瞻性收集2021年1月1日至2022年10月31日期间接受鼻内矫正手术的9例诊断为脑脊液鼻漏的患者的数据。术后至少一个月通过腰椎穿刺测量颅内压。比较术前和术后MRI扫描来评估变化。结果:术后腰穿刺显示67%的患者颅内压升高,100%的患者在MRI上显示持续的颅内高压征象。结论:处理脑脊液鼻漏患者颅内压升高应优先于手术矫正。对于典型IIH表型的患者,可能需要考虑永久性腹膜分流或药物治疗。纵向研究对于进一步了解长期结果至关重要。
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来源期刊
American Journal of Otolaryngology
American Journal of Otolaryngology 医学-耳鼻喉科学
CiteScore
4.40
自引率
4.00%
发文量
378
审稿时长
41 days
期刊介绍: Be fully informed about developments in otology, neurotology, audiology, rhinology, allergy, laryngology, speech science, bronchoesophagology, facial plastic surgery, and head and neck surgery. Featured sections include original contributions, grand rounds, current reviews, case reports and socioeconomics.
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