Extraction, Isolation and Purification of Catechins and their Applications.

IF 1.9 4区 医学 Q3 CHEMISTRY, MEDICINAL Medicinal Chemistry Pub Date : 2025-01-06 DOI:10.2174/0115734064353669241212064640
Hong-Mei Cao, Jiao-Jiao Fang, Yi-Tao Zhao, Pei-Hong Zhao, Xin Chen
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Abstract

Catechins, the main active components of tea polyphenols, boast remarkable antioxidant activities because of their unique structures. This translates to a range of potential health benefits, including fighting antibacterial, inflammation, and even cancers. However, extracting these beneficial compounds can be tricky as they're prone to degradation. Thankfully, recent advancements have yielded successful methods for isolating and purifying catechins, allowing us to obtain them in their purest form. The power of catechins isn't just theoretical. In vitro and in vivo studies have demonstrated promising results in treating various conditions like inflammation, cancer, neurodegenerative diseases, cardiovascular diseases, diabetes, and more. This review dives deep into the methods used to extract, isolate, and purify catechins. Additionally, it explores their potent antioxidant activities and exciting possibilities for future applications.

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儿茶素的提取、分离纯化及其应用。
儿茶素是茶多酚的主要活性成分,由于其独特的结构而具有显著的抗氧化活性。这转化为一系列潜在的健康益处,包括抗菌,炎症,甚至癌症。然而,提取这些有益的化合物可能很棘手,因为它们容易降解。值得庆幸的是,最近的进步已经产生了分离和纯化儿茶素的成功方法,使我们能够以最纯净的形式获得儿茶素。儿茶素的力量不仅仅是理论上的。体外和体内研究已经在治疗各种疾病,如炎症、癌症、神经退行性疾病、心血管疾病、糖尿病等方面显示出有希望的结果。本文对儿茶素的提取、分离和纯化方法进行了综述。此外,它还探讨了它们强大的抗氧化活性和未来应用的令人兴奋的可能性。
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来源期刊
Medicinal Chemistry
Medicinal Chemistry 医学-医药化学
CiteScore
4.30
自引率
4.30%
发文量
109
审稿时长
12 months
期刊介绍: Aims & Scope Medicinal Chemistry a peer-reviewed journal, aims to cover all the latest outstanding developments in medicinal chemistry and rational drug design. The journal publishes original research, mini-review articles and guest edited thematic issues covering recent research and developments in the field. Articles are published rapidly by taking full advantage of Internet technology for both the submission and peer review of manuscripts. Medicinal Chemistry is an essential journal for all involved in drug design and discovery.
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