Antioxidant, antibacterial, and systemic efficacy of sesame oil pulling in periodontitis and diabetes management.

IF 1.3 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Quintessence international Pub Date : 2025-03-18 DOI:10.3290/j.qi.b5923875

Nehil Saran, Rameshwari Singhal, Abbas Ali Mahdi, Deepak Bhaghchandani, Pavitra Rastogi, Nand Lal, Shivani Pandey, Supriya Bhalerao

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Abstract

Objective: To evaluate the efficacy of sesame oil pulling in periodontitis with/without type 2 diabetes mellitus (T2DM), compared to chlorhexidine, for its oral and systemic health benefits.

Method and materials: A total of 120 periodontitis patients, without (Group A; 60)/with (Group B; 60) T2DM, underwent control (chlorhexidine 0.12%; Group A1 and B1) and test (sesame oil pulling; Group A2 and B2) interventions. Plaque index, pocket depth, salivary total antioxidant capacity (T-AOC) enzyme-linked-immunosorbent-assay (ELISA), subgingival plaque BANA test, and serum C-reactive protein (CRP) were evaluated at baseline and 30 days post-intervention using analysis of variance (ANOVA) with a significant P value set at .05. Group B serum samples were also analyzed for fructosamine and lipid profile.

Results: Both treatment regimens were equivalent in reduction of plaque, pocket depth, and red complex periodontopathogens in Group A and B. Significant increase in salivary T-AOC post-intervention was observed in Group B with both interventions (P .01). Sesame oil pulling significantly decreased systemic CRP and triglyceride levels, with no difference observed with chlorhexidine in Group B.

Conclusion: Sesame oil pulling is equivalent to chlorhexidine for anti-plaque, antibacterial, and antioxidant effects in periodontitis patients with/without T2DM. Systemic anti-inflammatory, cardio-protective benefits (reduction of CRP and triglycerides) make it a better adjunct to scaling and root planing than chlorhexidine in periodontitis with T2DM.

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芝麻油拔除在牙周炎及糖尿病治疗中的抗氧化、抗菌及全身功效。

目的：评价香油拔除治疗伴有/不伴有2型糖尿病（T2DM）的牙周炎的疗效，并与氯己定比较其口腔和全身健康益处。材料与方法：120例牙周炎患者，无(A组；60)/与(B组；60) T2DM，对照组(氯己定0.12%；A1组和B1组)和试验(麻油拔；A2组和B2组)干预。采用方差分析（ANOVA）在基线和干预后30天评估斑块指数、口袋深度、唾液总抗氧化能力（T-AOC）酶联免疫吸附试验（ELISA）、龈下斑块BANA试验和血清CRP， p值为0.05。B组血清样品也分析果糖胺和脂质谱。结果：A组和B组两种治疗方案在减少牙菌斑、牙袋深度、红色复合牙周病原方面均相当。B组两种治疗方案干预后唾液T-AOC均显著增加(p结论：麻油拔除对伴有/非T2DM的牙周炎患者的抗牙菌斑、抗菌和抗氧化作用与氯己定相当。全身抗炎、保护心脏的益处（降低CRP和甘油三酯）使其更好地辅助氯己定治疗伴有T2DM的牙周炎。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Quintessence international 医学-牙科与口腔外科

CiteScore

3.30

自引率

5.30%

发文量

审稿时长

1 months

期刊介绍： QI has a new contemporary design but continues its time-honored tradition of serving the needs of the general practitioner with clinically relevant articles that are scientifically based. Dr Eli Eliav and his editorial board are dedicated to practitioners worldwide through the presentation of high-level research, useful clinical procedures, and educational short case reports and clinical notes. Rigorous but timely manuscript review is the first order of business in their quest to publish a high-quality selection of articles in the multiple specialties and disciplines that encompass dentistry.