{"title":"IGFBP6 contributes to vascular resilience","authors":"Martin A. Schwartz","doi":"10.1038/s44161-024-00597-8","DOIUrl":null,"url":null,"abstract":"Atherosclerosis and other vascular inflammatory diseases are determined by the balance between pro- and anti-inflammatory pathways. A report now identifies IGFBP6 as a component of an anti-inflammatory, protective program in vascular endothelial cells and demonstrates that major vault protein is the key downstream effector.","PeriodicalId":74245,"journal":{"name":"Nature cardiovascular research","volume":"4 2","pages":"122-123"},"PeriodicalIF":10.8000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature cardiovascular research","FirstCategoryId":"1085","ListUrlMain":"https://www.nature.com/articles/s44161-024-00597-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Atherosclerosis and other vascular inflammatory diseases are determined by the balance between pro- and anti-inflammatory pathways. A report now identifies IGFBP6 as a component of an anti-inflammatory, protective program in vascular endothelial cells and demonstrates that major vault protein is the key downstream effector.
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