Comparative evaluation of silver diamine fluoride, glass ionomer cement, and calcium hydroxide for indirect pulp therapy in young permanent molars: A randomized controlled trial.

Tejaswini M Ghorpade, Devendra P Patil, Farhin Alimiya Katge, Vamsi Krishna Chimata, Parin Bhanushali
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Abstract

Objectives: Comparative evaluation of indirect pulp therapy (IPT) with silver diamine fluoride (SDF), Type VII glass ionomer cement (GIC), and calcium hydroxide (Ca(OH)2) in young permanent molars.

Materials and methods: This was randomized controlled trial, in which 45 children with 60 young permanent first molars were allocated as; Group A: IPT with SDF, Group B: Type VII GIC, and Group C: Ca(OH)2. Clinical and radiographic evaluation and comparison was done at baseline, 3, 6, 12 months. Data analysis was done using Chi-square test, one way ANOVA, Tukey's post hoc analysis test. The level of significance was set at P < 0.05.

Results: On statistical analysis IPT with SDF showed 88.2%, Type VII GIC showed 94.1% and Ca(OH) 2 showed 88.2% success at 12 months' follow-up. However, intergroup comparison showed no statistical significant difference. The mean dentin bridge formation in SDF was 0.5467 ± 0.08338 mm, Type VII GIC (0.4813 ± 0.06551 mm) and Ca(OH)2 group (0.5 ± 0.07559 mm), which was statistically significant with a P = 0.049.

Conclusions: On comparative evaluation, clinical and radiographic success for IPT with SDF, Type VII GIC and Ca (OH) 2 were comparable. This study also concluded SDF and Type VII GIC can be used as IPT agents in permanent teeth. Dentin bridge formation was more in SDF followed by Ca(OH)2 and Type VII GIC, respectively.

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氟化二胺银、玻璃离子水门合剂和氢氧化钙间接牙髓治疗年轻恒磨牙的比较评价:一项随机对照试验。
目的:比较评价氟化二胺银(SDF)、VII型玻璃离子水门合剂(GIC)和氢氧化钙(Ca(OH)2)对幼龄恒磨牙间接牙髓治疗(IPT)的疗效。材料与方法:本试验为随机对照试验,45例儿童,60颗幼龄恒磨牙;A组:IPT伴SDF, B组:VII型GIC, C组:Ca(OH)2。在基线、3、6、12个月进行临床和影像学评估和比较。数据分析采用卡方检验、单因素方差分析、Tukey事后分析检验。P < 0.05为显著性水平。结果:随访12个月,IPT合并SDF的成功率为88.2%,VII型GIC的成功率为94.1%,Ca(OH) 2的成功率为88.2%。组间比较差异无统计学意义。SDF组牙本质桥形成平均为0.5467±0.08338 mm, VII型GIC组牙本质桥形成平均为0.4813±0.06551 mm, Ca(OH)2组牙本质桥形成平均为0.5±0.07559 mm,差异有统计学意义(P = 0.049)。结论:在比较评价中,IPT合并SDF、VII型GIC和Ca (OH) 2的临床和影像学成功率具有可比性。本研究还得出了SDF和VII型GIC可作为恒牙IPT剂的结论。牙本质桥的形成以SDF为主,其次是Ca(OH)2和VII型GIC。
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