Correction to “Controlled Release of Drugs from Gradient Hydrogels for High-Throughput Analysis of Cell–Drug Interactions”

IF 7.3 1区 化学 Q1 CHEMISTRY, ANALYTICAL Analytical Chemistry Pub Date : 2025-01-14 DOI:10.1021/acs.analchem.5c00172
Serge Ostrovidov, Nasim Annabi, Azadeh Seidi, Murugan Ramalingam, Fariba Dehghani, Hirokazu Kaji, Ali Khademhosseini
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Abstract

In the original version of this article, some of the representative live/dead images were inadvertently repeated in Figure 4B–D. These panels were composed of several individual images that the authors manually stacked together to display the entire hydrogel area from top to bottom. To validate our data, we repeated the experiments presented in Figure 4B–D and would like to include the new data to address this concern. The incorporation of these updated panels does not alter the interpretation of the data or the conclusions of the study but serves to confirm the accuracy of the published work by the authors. We apologize for this error. Figure 4. Effect of drug on cell viability. Fluorescent micrographs of 3T3 cells cultured in a multiwell plate and treated with (B) PEGDA hydrogel without OA (negative control), (C) with 2 μM OA (positive control), and (D) with an OA concentration gradient. Dead cells are marked in red by ethidium bromide, while living cells are marked in green by calcein-AM. This article has not yet been cited by other publications.

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对 "梯度水凝胶中药物的可控释放用于细胞-药物相互作用的高通量分析 "的更正
在本文的原始版本中,图4B-D无意中重复了一些具有代表性的活/死图像。这些面板由几个单独的图像组成,作者手动堆叠在一起,从上到下显示整个水凝胶区域。为了验证我们的数据,我们重复了图4B-D所示的实验,并希望包含新数据来解决这个问题。纳入这些更新的小组不会改变对数据的解释或研究的结论,但有助于确认作者发表的工作的准确性。我们为这个错误道歉。图4。药物对细胞活力的影响。多孔板培养3T3细胞,(B)无OA水凝胶处理(阴性对照),(C) 2 μM OA水凝胶处理(阳性对照),(D) OA浓度梯度处理(阳性对照)。死细胞用溴化乙锭标记为红色,活细胞用钙黄素- am标记为绿色。这篇文章尚未被其他出版物引用。
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来源期刊
Analytical Chemistry
Analytical Chemistry 化学-分析化学
CiteScore
12.10
自引率
12.20%
发文量
1949
审稿时长
1.4 months
期刊介绍: Analytical Chemistry, a peer-reviewed research journal, focuses on disseminating new and original knowledge across all branches of analytical chemistry. Fundamental articles may explore general principles of chemical measurement science and need not directly address existing or potential analytical methodology. They can be entirely theoretical or report experimental results. Contributions may cover various phases of analytical operations, including sampling, bioanalysis, electrochemistry, mass spectrometry, microscale and nanoscale systems, environmental analysis, separations, spectroscopy, chemical reactions and selectivity, instrumentation, imaging, surface analysis, and data processing. Papers discussing known analytical methods should present a significant, original application of the method, a notable improvement, or results on an important analyte.
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