Synthesis of 2-amino-1-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-4-oxo-4,5-dihydro-1H-pyrrole-3-carboxylic acid derivatives and studies of their antitumor activity against melanoma cell line B16-F10
I. A. Gorbunova, A. Rogova, K. Yu. Parkhoma, D. A. Shipilovskikh, T. E. Karpov, R. R. Makhmudov, A. S. Timin, S. A. Shipilovskikh
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引用次数: 0
Abstract
A range of new derivatives of 2-amino-4-oxo-1-(3-cyano-4,5,6,7-tetrahydrobenzo[b]-thiophen-2-yl)-4,5-dihydro-1H-pyrrole-3-carboxylic acids bearing the nitrile group at the position 3 of the thiophene ring was broadened. Antitumor activity against the B16-F10 murine melanoma cell line was studied.
期刊介绍：
Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections:
General and Inorganic Chemistry;
Physical Chemistry;
Organic Chemistry;
Organometallic Chemistry;
Chemistry of Natural Compounds and Bioorganic Chemistry.
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