Treatment of gingival recession with vestibular incision subperiosteal tunnel access and advanced platelet-rich fibrin.

IF 2.6 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE BMC Oral Health Pub Date : 2025-01-14 DOI:10.1186/s12903-024-05398-w
Marwa Abdelhaleem, Wafaa Saleh, Samah Elmeadawy
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Abstract

Objectives: The current literature about the effect of advanced platelet rich fibrin(A-PRF) with vestibular incision subperiosteal tunnel access (VISTA) technique in treating gingival recession is scarce. Therefore, the aim of the current randomized clinical trial is to evaluate the effect of A-PRF with VISTA technique in the treatment of Cairo class 1 gingival recession (RT1).

Methods: Twenty-four patients who met the eligibility criteria were randomly allocated into two groups. VISTA + A-PRF was the treatment of the study group, while VISTA + collagen matrix was performed for the control group. The clinical outcomes were assessed by a single-blind assessor at baseline, three months, and six months. They were divided into primary and secondary outcomes. The primary outcomes included recession depth (RD), recession width (RW), gingival thickness (GT), mean of root coverage % (MRC%), and width of attached gingiva (WAG) while the secondary outcome included clinical attachment level (CAL).

Results: The primary outcomes analysis demonstrated statistically significant improvements in RD, RW, MRC%, GT, and WAG after 3 and 6 months in both groups (p < 0.001). However, the study group demonstrated a significantly greater improvement than the control group in RD, RW, and MRC%. No significant differences were observed between the two groups regarding GT and WAG.

Conclusions: Both treatment approaches were effective in the treating of RT1 adjacent gingival recessions. A-PRF showed promising results compared to collagen matrix.

Trial registration: The current randomized clinical trial was registered at ClinicalTrials.gov (Registration number: NCT06357351) and it was released on 10/04/2024.

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前庭切口骨膜下隧道入路及晚期富血小板纤维蛋白治疗牙龈萎缩。
目的:目前关于先进富血小板纤维蛋白(A-PRF)联合前庭切口骨膜下隧道通路(VISTA)技术治疗牙龈退缩的文献很少。因此,本随机临床试验的目的是评价A-PRF联合VISTA技术治疗Cairo 1级牙龈衰退(RT1)的效果。方法:24例符合入选标准的患者随机分为两组。实验组采用VISTA + A-PRF治疗,对照组采用VISTA +胶原基质治疗。临床结果由单盲评估者在基线、3个月和6个月进行评估。他们被分为主要和次要结果。主要指标包括退退深度(RD)、退退宽度(RW)、牙龈厚度(GT)、平均牙根覆盖% (MRC%)和附着龈宽度(WAG),次要指标包括临床附着水平(CAL)。结果:主要结局分析显示,两组患者在3个月和6个月后RD、RW、MRC%、GT和WAG均有统计学意义的改善(p)。结论:两种治疗方法对RT1相邻牙龈衰退均有效。与胶原基质相比,A-PRF显示出良好的效果。试验注册:目前的随机临床试验已在ClinicalTrials.gov注册(注册号:NCT06357351),并于2024年4月10日发布。
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来源期刊
BMC Oral Health
BMC Oral Health DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
3.90
自引率
6.90%
发文量
481
审稿时长
6-12 weeks
期刊介绍: BMC Oral Health is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of disorders of the mouth, teeth and gums, as well as related molecular genetics, pathophysiology, and epidemiology.
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