Neuropsychiatric symptoms and specific cognitive domains in mild cognitive impairment.

Q3 Medicine Dementia e Neuropsychologia Pub Date : 2025-01-13 eCollection Date: 2024-01-01 DOI:10.1590/1980-5764-DN-2024-0187

Lucas Luchesi Barnes, Lucas Francisco Botequio Mella, Francisca Daniele Ferreira Lopes, Amilton Dos Santos, Paulo Dalgalarrondo

{"title":"Neuropsychiatric symptoms and specific cognitive domains in mild cognitive impairment.","authors":"Lucas Luchesi Barnes, Lucas Francisco Botequio Mella, Francisca Daniele Ferreira Lopes, Amilton Dos Santos, Paulo Dalgalarrondo","doi":"10.1590/1980-5764-DN-2024-0187","DOIUrl":null,"url":null,"abstract":"Neuropsychiatric symptoms (NPS) such as depression, anxiety, and apathy are present in mild cognitive impairment (MCI) and are risk factors for cognitive decline. However, the relationship between NPS and specific cognitive domains is less clear.Objective: This study aimed to assess whether there is a correlation between NPS and specific cognitive domains.Methods: A cross-sectional study which included 174 participants with MCI, aged 55 years or older. Differences in sociodemographic profile, neuroimaging, and neuropsychological tests between MCI participants with and without NPS were measured.Results: Participants with NPS had lower education and worse performance in attention tests and executive functions. Psychotic symptoms were correlated with deficits in visuospatial functions; irritability and agitation with inattention and deficit of inhibitory control; and depression with inattention.Conclusion: Correlations were found between some NPS with specific cognitive domains, especially psychotic symptoms, but also agitation, irritability, apathy, and depression.","PeriodicalId":39167,"journal":{"name":"Dementia e Neuropsychologia","volume":"18 ","pages":"e20240187"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729349/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dementia e Neuropsychologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/1980-5764-DN-2024-0187","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Neuropsychiatric symptoms (NPS) such as depression, anxiety, and apathy are present in mild cognitive impairment (MCI) and are risk factors for cognitive decline. However, the relationship between NPS and specific cognitive domains is less clear.

Objective: This study aimed to assess whether there is a correlation between NPS and specific cognitive domains.

Methods: A cross-sectional study which included 174 participants with MCI, aged 55 years or older. Differences in sociodemographic profile, neuroimaging, and neuropsychological tests between MCI participants with and without NPS were measured.

Results: Participants with NPS had lower education and worse performance in attention tests and executive functions. Psychotic symptoms were correlated with deficits in visuospatial functions; irritability and agitation with inattention and deficit of inhibitory control; and depression with inattention.

Conclusion: Correlations were found between some NPS with specific cognitive domains, especially psychotic symptoms, but also agitation, irritability, apathy, and depression.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

轻度认知障碍的神经精神症状和特定认知领域。

神经精神症状（NPS），如抑郁、焦虑和冷漠存在于轻度认知障碍（MCI）中，是认知能力下降的危险因素。然而，NPS与特定认知领域之间的关系尚不清楚。目的：本研究旨在评估NPS与特定认知领域之间是否存在相关性。方法：一项横断面研究，包括174名年龄在55岁或以上的轻度认知障碍患者。测量了有和没有NPS的MCI参与者在社会人口学特征、神经影像学和神经心理学测试方面的差异。结果：NPS患者受教育程度较低，注意力测试和执行功能表现较差。精神症状与视觉空间功能缺陷相关；烦躁不安伴注意力不集中和抑制控制缺陷；注意力不集中导致抑郁。结论：某些NPS与特定的认知领域，特别是精神病性症状，以及躁动、易怒、冷漠和抑郁之间存在相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Dementia e Neuropsychologia Medicine-Geriatrics and Gerontology

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.