EBUS-guided Iodine-125 seed implantation in lymph node as a novel therapy for MCAO: A case report.

IF 1.3 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Medicine Pub Date : 2025-01-17 DOI:10.1097/MD.0000000000041198
Huiwen Qian, Jianqiang Jin, Changguo Wang, Yuting Wang, Juxiang Ge, Jianan Huang, Cheng Ji
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Abstract

Rationale: We report here a case of using iodine-125 (125I) seed implantation via endobronchial ultrasound (EBUS) in the treatment of malignant central airway obstruction (MCAO) in a patient with lung adenocarcinoma.

Patient concerns: The patient still experienced MCAO after conventional bronchoscopic interventional therapy.

Diagnoses: The patient was diagnosed as lung adenocarcinoma stage IV (T4N2M1a).

Interventions: She received implantation of radioactive 125I seeds in the lesion inside the right middle lobe bronchus and 12R lymph node via bronchoscopy and EBUS, in combination with chemotherapy and immunotherapy.

Outcomes: The patient's MCAO has been effectively controlled.

Lessons: The success of this case suggests that EBUS-guided 125I seed implantation to lymph nodes is a safe and effective therapeutic option for MCAO.

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ebus引导下淋巴结碘125粒子植入治疗MCAO的新方法1例。
理由:我们在此报告一例经支气管内超声(EBUS)使用碘-125 (125I)粒子植入治疗肺腺癌患者的恶性中央气道阻塞(MCAO)。患者注意事项:患者经常规支气管镜介入治疗后仍出现MCAO。诊断:患者诊断为肺腺癌IV期(T4N2M1a)。干预措施:经支气管镜及EBUS在右侧支气管中叶病变及12R淋巴结内植入放射性125I粒子,并联合化疗及免疫治疗。结果:患者MCAO得到有效控制。经验教训:本病例的成功提示ebus引导的125I粒子植入淋巴结是MCAO安全有效的治疗选择。
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来源期刊
Medicine
Medicine 医学-医学:内科
CiteScore
2.80
自引率
0.00%
发文量
4342
审稿时长
>12 weeks
期刊介绍: Medicine is now a fully open access journal, providing authors with a distinctive new service offering continuous publication of original research across a broad spectrum of medical scientific disciplines and sub-specialties. As an open access title, Medicine will continue to provide authors with an established, trusted platform for the publication of their work. To ensure the ongoing quality of Medicine’s content, the peer-review process will only accept content that is scientifically, technically and ethically sound, and in compliance with standard reporting guidelines.
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