Haoyu Jin, Min Zeng, Shouliang Wang, Yitian Ding, Suyang Chen, Jinxi Feng, Xianhao Chen, Tingting Miao, Fen Wu, Qian Shi
{"title":"Base-Promoted Tandem Synthesis of 6-H-Phenanthridine and its Derivatives","authors":"Haoyu Jin, Min Zeng, Shouliang Wang, Yitian Ding, Suyang Chen, Jinxi Feng, Xianhao Chen, Tingting Miao, Fen Wu, Qian Shi","doi":"10.1002/ejoc.202401334","DOIUrl":null,"url":null,"abstract":"<p>Herein, we proposed a simple approach for synthesizing 6-<i>H</i>-phenanthridine through, which was a tandem reaction and promoted by base. 2′-Fluoro-[1,1′-biphenyl]-2-carbaldehydes and LiN(SiMe<sub>3</sub>)<sub>2</sub> were simply added and combined to obtain different structures of 6-<i>H</i>-phenanthridines (26 examples, ≤90 % yield). In the syntheses of 6-<i>H</i>-phenaridine, the transition metal-free approach outlined in this paper is direct, convenient and easy to execute.</p>","PeriodicalId":167,"journal":{"name":"European Journal of Organic Chemistry","volume":"28 10","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202401334","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Herein, we proposed a simple approach for synthesizing 6-H-phenanthridine through, which was a tandem reaction and promoted by base. 2′-Fluoro-[1,1′-biphenyl]-2-carbaldehydes and LiN(SiMe3)2 were simply added and combined to obtain different structures of 6-H-phenanthridines (26 examples, ≤90 % yield). In the syntheses of 6-H-phenaridine, the transition metal-free approach outlined in this paper is direct, convenient and easy to execute.
期刊介绍：
The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies.
The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry:
Liebigs Annalen
Bulletin des Sociétés Chimiques Belges
Bulletin de la Société Chimique de France
Gazzetta Chimica Italiana
Recueil des Travaux Chimiques des Pays-Bas
Anales de Química
Chimika Chronika
Revista Portuguesa de Química
ACH—Models in Chemistry
Polish Journal of Chemistry.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
