Significant Calcification of an Entire Aortic Tree with Renal Artery Subocclusion: Acute Kidney Injury, Ischemic Kidney Disease, and the Tissue Viability Question-A Case Report.

IF 3.4 3区 生物学 Q1 BIOLOGY Life-Basel Pub Date : 2025-01-11 DOI:10.3390/life15010082
Marko Baralić, Selena Gajić, Aleksandra Kezić, Ana Bontić, Jelena Pavlović, Voin Brković, Vidna Karadžić Ristanović, Danka Bjelić, Maja Životić, Sanja Radojević-Škodrić, Želimir Antonić, Nenad Ilijevski, Milan Radović
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Abstract

Background: Undiagnosed and untreated atherosclerotic renal artery stenosis (ARAS) can result in end-stage kidney disease (ESKD). To obtain an accurate diagnosis, it is crucial to recognize the symptoms and signs suggesting renal artery stenosis (RAS) and perform appropriate diagnostic and treatment procedures afterward.

Case presentation: We present a case of a 60-year-old female patient with hypertensive crisis, acute heart failure (HF), and pulmonary edema as the initial signs of acute kidney injury (AKI) caused by right RAS and left renal artery occlusion in the presence of severe aortic atherosclerosis revealed on computed tomography angiography (CTA) of the abdomen. The patient's renal function recovered completely following percutaneous transluminal angioplasty (PTA) with stent implantation in the right renal artery at the site of subocclusion.

Conclusions: Even in patients with concomitant disorders like type-2 diabetes mellitus (T2DM), hypertension (HTN), or HF, the dilatation of significantly narrowed renal arteries due to severe calcifications can result in complete renal function recovery.

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全主动脉树明显钙化伴肾动脉亚闭塞:急性肾损伤、缺血性肾病和组织活力问题——一例报告。
背景:未经诊断和治疗的动脉粥样硬化性肾动脉狭窄(ARAS)可导致终末期肾病(ESKD)。为了获得准确的诊断,识别提示肾动脉狭窄(RAS)的症状和体征并进行适当的诊断和治疗程序是至关重要的。病例介绍:我们报告一例60岁女性高血压危象,急性心力衰竭(HF)和肺水肿作为急性肾损伤(AKI)的初始症状,由右侧RAS和左侧肾动脉闭塞引起,腹部计算机断层血管造影(CTA)显示存在严重的主动脉粥样硬化。经皮腔内血管成形术(PTA)并在右肾动脉亚闭区植入支架后,患者肾功能完全恢复。结论:即使在伴有2型糖尿病(T2DM)、高血压(HTN)、HF等疾病的患者中,由于严重钙化导致的肾动脉明显狭窄的扩张也可以导致肾功能的完全恢复。
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来源期刊
Life-Basel
Life-Basel Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
4.30
自引率
6.20%
发文量
1798
审稿时长
11 weeks
期刊介绍: Life (ISSN 2075-1729) is an international, peer-reviewed open access journal of scientific studies related to fundamental themes in Life Sciences, especially those concerned with the origins of life and evolution of biosystems. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers.
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