Efficiency of indocyanine green fluorescence assisted laparoscopic hepatectomy in patients with hepatocellular carcinoma.

IF 1.2 4区医学 Q2 MEDICINE, GENERAL & INTERNAL Pakistan Journal of Medical Sciences Pub Date : 2025-01-01 DOI:10.12669/pjms.41.1.10626

Wei Feng, Xiaoxiao Xiong, Qile Wang, Siying Chen, Yao Ma, Dongming Zhu

{"title":"Efficiency of indocyanine green fluorescence assisted laparoscopic hepatectomy in patients with hepatocellular carcinoma.","authors":"Wei Feng, Xiaoxiao Xiong, Qile Wang, Siying Chen, Yao Ma, Dongming Zhu","doi":"10.12669/pjms.41.1.10626","DOIUrl":null,"url":null,"abstract":"Objective: To analyze the efficacy of indocyanine green fluorescence (ICG-F)-assisted laparoscopic hepatectomy in patients with hepatocellular carcinoma (HCC).Methods: This retrospective study included 120 patients with HCC who underwent laparoscopic hepatectomy in The First Affiliated Hospital of Soochow University from February 2020 to November 2022. Among them, 58 patients underwent conventional laparoscopic surgery (laparoscopic group), and 62 patients underwent ICG-F assisted laparoscopic surgery (ICG-F group). The perioperative conditions, levels of inflammatory factors before and after the operation, levels of liver function indexes, and incidence of complications in the two groups were statistically analyzed.Results: The perioperative indexes of patients in the ICG-F group improved compared to the laparoscopic group (P<0.05). On the second day after the operation, the inflammatory response in the two groups was significantly higher than before the operation and significantly lower in the ICG-F group compared to the laparoscopic group (P<0.05). Liver function of the two groups decreased two days after the surgery and was markedly lower in the ICG-F group than the laparoscopic group (P<0.05). The incidence of complications in the ICG-F group was significantly lower than that in the laparoscopic group (P<0.05).Conclusions: Compared with conventional laparoscopic surgery, ICG-F-assisted laparoscopic hepatectomy for HCC can reduce surgical injury, alleviate the degree of inflammatory response, protect patients' liver function, and significantly reduce the risk of complications.","PeriodicalId":19958,"journal":{"name":"Pakistan Journal of Medical Sciences","volume":"41 1","pages":"119-124"},"PeriodicalIF":1.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755307/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12669/pjms.41.1.10626","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To analyze the efficacy of indocyanine green fluorescence (ICG-F)-assisted laparoscopic hepatectomy in patients with hepatocellular carcinoma (HCC).

Methods: This retrospective study included 120 patients with HCC who underwent laparoscopic hepatectomy in The First Affiliated Hospital of Soochow University from February 2020 to November 2022. Among them, 58 patients underwent conventional laparoscopic surgery (laparoscopic group), and 62 patients underwent ICG-F assisted laparoscopic surgery (ICG-F group). The perioperative conditions, levels of inflammatory factors before and after the operation, levels of liver function indexes, and incidence of complications in the two groups were statistically analyzed.

Results: The perioperative indexes of patients in the ICG-F group improved compared to the laparoscopic group (P<0.05). On the second day after the operation, the inflammatory response in the two groups was significantly higher than before the operation and significantly lower in the ICG-F group compared to the laparoscopic group (P<0.05). Liver function of the two groups decreased two days after the surgery and was markedly lower in the ICG-F group than the laparoscopic group (P<0.05). The incidence of complications in the ICG-F group was significantly lower than that in the laparoscopic group (P<0.05).

Conclusions: Compared with conventional laparoscopic surgery, ICG-F-assisted laparoscopic hepatectomy for HCC can reduce surgical injury, alleviate the degree of inflammatory response, protect patients' liver function, and significantly reduce the risk of complications.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

求助全文

约1分钟内获得全文去求助

来源期刊

Pakistan Journal of Medical Sciences 医学-医学：内科

CiteScore

4.10

自引率

9.10%

发文量

363

审稿时长

3-6 weeks

期刊介绍： It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.