68 Ga-FAPI-04 Versus 18 F-FDG PET/CT in Duodenal Synovial Sarcoma.

IF 9.6 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-08-01 Epub Date: 2025-01-30 DOI:10.1097/RLU.0000000000005706
Fenglin Zhan, Xin Liu, Hangcheng Zhou, Xuemei Wang, Xiaobo Yao
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Abstract

Abstract: A previously healthy 18-year-old man with a 9-month history of upper abdominal pain and significant weight loss underwent gastroscopy, revealing an ulcerative lesion in the duodenal bulb. Enrolled in a clinical trial, both 18 F-FDG and 68 Ga-FAPI-04 PET/CT demonstrated similar metabolic activity, though 68 Ga-FAPI-04 offered superior lesion delineation. Pathology confirmed synovial sarcoma. This case highlights the potential utility of 68 Ga-FAPI-04 as a radiopharmaceutical for evaluating rare gastrointestinal synovial sarcomas.

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68Ga-FAPI-04与18F-FDG在十二指肠滑膜肉瘤中的PET/CT对比
摘要:一名既往健康的18岁男性,有9个月的上腹痛病史,体重明显下降,接受胃镜检查,发现十二指肠球部溃疡病变。在一项临床试验中,18F-FDG和68Ga-FAPI-04 PET/CT显示出相似的代谢活性,尽管68Ga-FAPI-04提供了更好的病变描绘。病理证实为滑膜肉瘤。该病例强调了68Ga-FAPI-04作为一种放射性药物用于评估罕见的胃肠道滑膜肉瘤的潜在用途。
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来源期刊
Clinical Nuclear Medicine
Clinical Nuclear Medicine 医学-核医学
CiteScore
2.90
自引率
31.10%
发文量
1113
审稿时长
2 months
期刊介绍: Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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